摘要
Objective To understand the distribution of the average glandular dose(AGD) in mammography by investigating 1,828 exposure parameters of 8 mammography machines in three cities, by using random sampling. Methods A survey of 8 mammography machines in three different cities, sampled using stratified random sampling methods, was performed, and 1,828 mammography exposure parameters were recorded. Incident air kerma(k) was measured by Quality-Assurance(QA) dosimeters, and AGD was calculated by series conversion coefficients based on a 3D detailed Monte Carlo breast model, published by Wang et al. Results The distribution of compressed breast thickness(CBT) fitted a normal distribution, while that of AGD fitted a skewed distribution. The mean value of CBT in a medio-lateral oblique(MLO) view was about 5.6% higher than that in the craniocaudal(CC) view, with significant statistical difference; mean value of AGD and CBT in the sample was 1.3 mGy and 4.6 cm, respectively. The AGD trended upward with increasing CBT, similar to the results of other researches. Conclusion The mean AGD and CBT levels in our study for mammography practice in China were 1.3 mGy and 4.6 cm, respectively. AGD is influenced by manufacturer-specific variation as machine response to CBT changes and target/filter combination. The present study can provide evidence for establishing a diagnostic reference level in China.
Objective To understand the distribution of the average glandular dose(AGD) in mammography by investigating 1,828 exposure parameters of 8 mammography machines in three cities, by using random sampling. Methods A survey of 8 mammography machines in three different cities, sampled using stratified random sampling methods, was performed, and 1,828 mammography exposure parameters were recorded. Incident air kerma(k) was measured by Quality-Assurance(QA) dosimeters, and AGD was calculated by series conversion coefficients based on a 3D detailed Monte Carlo breast model, published by Wang et al. Results The distribution of compressed breast thickness(CBT) fitted a normal distribution, while that of AGD fitted a skewed distribution. The mean value of CBT in a medio-lateral oblique(MLO) view was about 5.6% higher than that in the craniocaudal(CC) view, with significant statistical difference; mean value of AGD and CBT in the sample was 1.3 mGy and 4.6 cm, respectively. The AGD trended upward with increasing CBT, similar to the results of other researches. Conclusion The mean AGD and CBT levels in our study for mammography practice in China were 1.3 mGy and 4.6 cm, respectively. AGD is influenced by manufacturer-specific variation as machine response to CBT changes and target/filter combination. The present study can provide evidence for establishing a diagnostic reference level in China.
基金
supported by the Jiangsu Province’s Outstanding Medical Academic Leader Program [CXTDA2017029]
Jiangsu Province's Key Medical Discipline of Epidemiology [ZDXK A 2016008]
Science and education strong industry engineering youth talent project [JKRC2016014]
Jiangsu Provincial preventive medicine research project [Y2018082]