中医辨证施治联合西医常规治疗急性肠胃炎的疗效及对炎症因子水平的影响

Effect of Syndrome Differentiation Therapy Combined with Western Medicine on Acute Gastroenteritis and Its Influence on Inflammatory Factors

目的:探讨中医辨证施治联合西医常规治疗急性肠胃炎的临床疗效,并分析对炎症因子水平影响。方法:选取2014年3月—2017年12月该院收治的急性肠胃炎患者198例为研究对象,随机分为治疗组与对照组,各99例,对照组患者给予西医常规治疗,治疗组患者在此基础上给予中医辨证施治,对比两组患者临床疗效、症状缓解时间、治疗前后主要症状评分及炎症因子水平变化,并观察两组患者不良反应发生情况。结果:治疗组患者的总有效率明显高于对照组(P <0. 05);治疗组患者腹泻、腹痛、发热、呕吐消失时间明显较对照组缩短(P <0. 05);治疗后,两组患者的大便性状、大便次数、腹痛症状评分均较治疗前降低,且治疗组患者的大便性状、大便次数、腹痛症状评分低于对照组(P <0. 05);治疗后,两组患者的IL-6、TNF-α、CRP水平均较治疗前明显降低,且治疗组患者的IL-6、TNF-α、CRP水平明显低于对照组(P <0. 05);两组患者不良反应发生率比较无明显差异(P> 0. 05)。结论:中医辨证施治联合西医常规治疗急性肠胃炎临床疗效显著,可有效改善患者临床症状,减轻炎症反应,值得临床推广。

Objective: To investigate the clinical efficacy of TCM syndrome differentiation and treatment combined with conventional western medicine in the treatment of acute gastroenteritis and analyze the impact on the levels of inflammatory factors. Methods: A total of 198 patients with acute gastroenteritis in our hospital in March 2014-December 2017 were selected as the research subjects. They were randomly divided into the treatment group and the control group,each with 99 cases. The control group was given conventional treatment with western medicine. On the basis,the patients in the treatment group were treated with TCM syndrome differentiation,and the clinical efficacy and symptom relief time of the two groups were compared. Before and after treatment,the main symptom score and inflammatory factor levels were observed and the incidence of adverse reactions in the two groups was observed. Results: The total effective rate in the treatment group was significantly higher than that in the control group( P < 0. 05). The time of diarrhea,abdominal pain,fever and vomiting in the treatment group were significantly shorter than those in the control group( P < 0. 05). The scores of abdominal pain symptoms were lower than those before treatment and the stool traits,defecation times and abdominal pain symptom scores in the treatment group were lower than those in the control group( P <0. 05),and the levels of IL-6,TNF-α and CRP in the two groups were significantly lower than those before treatment. The levels of IL-6,TNF-α and CRP in the treatment group was significantly lower than that in the control group( P < 0. 05). There was no significant difference in the incidence of adverse reactions between the two groups( P > 0. 05). Conclusion: The clinical curative effect of TCM syndrome differentiation therapy combined with routine western medicine in treating acute gastroenteritis is remarkable. It can effectively improve the clinical symptoms of patients and alleviate inflammatory reaction. It is worthy of popularizing.