十七味补肾益精丸的研制与临床疗效观察

Development and effective observation on Shiqiwei Bushen Yijing Wan

目的:十七味补肾益精丸的研制与临床疗效观察。方法:选取248例少弱精症患者随机分成两组,分别用十七味补肾益精丸和维生素E对进行治疗,三个月后观察治疗前后两组精子浓度、精子活力,血清卵泡生成激素(Follicle Stimulating Hormone,FSH)、睾酮(Teststerone,T)、促黄体生成素(Luteinizing Hormone,LH)水平。结果:十七味补肾益精丸能显著改善精子浓度和活力,血清FSH明显降低,T显著升高。结论:十七味补肾益精丸能明显改善男性少弱精子症的精子质量,其作用机制应是多层次、等环节、多途径相互影响作用的结果,多年来,未发现在使用过程中的不良反应发生,临床使用安全有效,值得进一步推广。

Objective:To study the preparation and clinical efficacy of Shiqiwei Bushen Yijing Wan (十七味补肾益精丸).Methods: 248 patients with oligoasthenozoospermia were randomly divided into two groups,and the patients were treated with Shiqiwei Bushen Yijing Wan or vitamin E.After 3 months,the sperm concentration,sperm motility,serum FSH,T and LH levels in two groups before and after treatment were observed.Results:Shiqiwei Bushen Yijing Wan can significantly improve sperm concentration and vitality,serum FSH level is significantly reduced,and T level is significantly increased.Conclusion:Shiqiwei Bushen Yijing Wan can significantly improve the sperm quality of patients with oligozoospermia,is safe and effective,is worth further promotion.