摘要
以五氧化二碘为自由基引发剂和碘源,炔烃和磺酰肼为反应原料,发展了一种高效的自由基碘磺酰化反应合成(E)-β-碘代烯基砜方法.在温和的条件下,能以良好到优秀的收率得到结构多样的β-碘代烯基砜类化合物.与文献报道方法相比,该方法无需过氧化物条件即可完成,更加绿色环保.
A facile and efficient I2O5 promoted iodosulfonylation of alkynes for direct synthesis of(E)-β-iodovinyl sulfones is described.This procedure affords various synthetically usefulβ-iodosulfonyl alkenes in moderate to good yields under peroxide free conditions.
作者
唐裕才
冉书童
王萍
陈飘
Tang Yucai;Ran Shutong;Wang Ping;Chen Piao(College of Chemistry and Materials Engineering,Hunan University of Arts and Science,Changde 415000;Hunan Province Cooperative Innovation Center for the Construction & Development of Dongting Lake Ecologic Economic Zone,Changde 415000)
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2019年第4期1116-1121,共6页
Chinese Journal of Organic Chemistry
基金
Project supported by the Start-up Foundation for Doctors of Hunan University of Arts and Science(No.17BSQD32)
the Construct Program of the Key Discipline in Hunan Province(Applied Chemistry)~~
