摘要
芳基磺酰肼在四丁基碘化铵/盐酸体系作用下和4-羟基香豆素发生硫醚化反应,以65%~94%的产率得到了一系列3-芳巯基-4-羟基香豆素化合物.该方法具有较广的底物普适性、原料来源广泛且易得、操作简便和产物产率高等优点.
A facile approach for thioetherification of 4-hydroxycoumarins with arylsulfonyl hydrazides promoted by tetrabutylammonium iodide in the presence of hydrochloric acid was developed generating a series of 3-arylthio-4-hydroxycoumarins in 65%~94%yields.Broad scope and easy availability of substrates,simple operation and high yields of products are the advantages of this method.
作者
朱福元
王彦梅
何明闯
严兆华
林森
Zhu Fuyuan;Wang Yanmei;He Mingchuang;Yan Zhaohua;Lin Sen(College of Chemistry,Nanchang University,Nanchang 330031)
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2019年第4期1175-1180,共6页
Chinese Journal of Organic Chemistry
基金
国家自然科学基金(No.21362022)资助项目~~
关键词
芳基磺酰肼
4-羟基香豆素
硫醚化反应
四丁基碘化铵
arylsulfonyl hydrazide
4-hydroxycoumarin
thioetherification
tetrabutylammonium iodide