四丁基碘化铵促进芳基磺酰肼和4-羟基香豆素的硫醚化反应

Tetrabutylammonium Iodide Promoted Thioetherification of Arylsulfonylhydrazides with 4-Hydroxycoumarins

芳基磺酰肼在四丁基碘化铵/盐酸体系作用下和4-羟基香豆素发生硫醚化反应,以65%~94%的产率得到了一系列3-芳巯基-4-羟基香豆素化合物.该方法具有较广的底物普适性、原料来源广泛且易得、操作简便和产物产率高等优点.

A facile approach for thioetherification of 4-hydroxycoumarins with arylsulfonyl hydrazides promoted by tetrabutylammonium iodide in the presence of hydrochloric acid was developed generating a series of 3-arylthio-4-hydroxycoumarins in 65%~94%yields.Broad scope and easy availability of substrates,simple operation and high yields of products are the advantages of this method.