Se粉为原料的芳硒基取代黄酮衍生物的合成（英文）

Synthesis of Ar Se-Substituted Flavone Derivatives Using Se Powder

新结构的黄酮衍生物,由于其多样化的生物活性而在药物发展中备受人们的重视.这里,报道了一种以Se粉为原料,使用铜化合物作为催化剂,通过C-H官能化来合成含ArSe取代基的黄酮衍生物,反应具有良好的选择性和较高的收率.

New flavone derivatives are highly valued in drug discovery due to their diversity of important bioactivities.Herein,one simple Cu-catalyzed method of constructing C-Se bonds on flavone structures using convenient Se powder via C-H functionalization is reported,regioselectively affording ArSe-substituted flavone derivatives in good yields.