亚甲蓝混合液联合中药痔瘘祛毒熏洗剂对混合痔外剥内扎术后患者的镇痛作用

Analgesic Efficacy of Methylene Blue Mixture Combined with Hemorrhoid Fistula Detoxification Lotion in Mixed Hemorrhoid Patients After Milligant-morgant Hemorrhoidectomy

【目的】探讨亚甲蓝混合液联合中药痔瘘祛毒熏洗剂对混合痔外剥内扎术后患者的镇痛效果。【方法】将100例腰麻下行混合痔外剥内扎术的患者随机分为治疗组和对照组,每组各50例。2组患者均于手术结束时,在手术创缘注射亚甲蓝混合液,治疗组应用中药痔瘘祛毒熏洗剂坐浴,对照组应用温水坐浴。观察2组患者术后第1、2、3天排便状态下数字评分法(NRS)疼痛评分情况,以及术后追加止痛药物和尿潴留发生情况。【结果】(1)术后第1、2、3天,治疗组的NRS疼痛评分均低于对照组(P<0.01)。(2)治疗组患者术后追加止痛药物有5例(占10.0%),明显少于对照组的11例(占22.0%),差异有统计学意义(P<0.01)。(3)治疗组术后尿潴留发生率为26.0%,略低于对照组的30.0%,但组间比较,差异无统计学意义(P>0.05)。(4)治疗期间,2组患者均未见明显的不良反应。【结论】亚甲蓝混合液联合中药痔瘘祛毒熏洗剂治疗混合痔外剥内扎术后患者,镇痛效果理想,术后尿潴留发生率低,安全有效。

Objective To investigate the analgesic efficacy of methylene blue mixture combined with Hemorrhoid Fistula Detoxification Lotion in mixed hemorrhoid patients after Milligant-morgant hemorrhoidectomy. Methods One hundred mixed hemorrhoid patients after Milligant-morgant hemorrhoidectomy under lumbar anesthesia were randomized into treatment group and control group,50 cases in each group. At the end of the operation,the two groups were injected with methylene blue mixture around the surgical wound, and additionally, the treatment group was given sitz bath with Chinese herbal medicine of Hemorrhoid Fistula Detoxification Lotion and the control group was given sitz bath with warm water. The defecation pain on the 1 st,2 nd,and 3 rd day after the operation in the two groups was evaluated with the scores of Numeric Rating Scale(NRS). Moreover,the additional use of analgesic drugs and incidence of urinary retention after the operation in the two groups were observed. Results(1)On the 1 st,2 nd,and 3 rd day after the operation,the NRS defecation pain scores in the treatment group were lower than those in the control group(P<0.01).(2)The additional use of analgesic drugs after the operation occurred in 5 cases(10.0%)from the treatment group and in 11 cases(22.0%)from the control group, the difference being statistically significant(P<0.01).(3)The incidence of urinary retention after the operation in the treatment group was 26.0%,mildly lower than that in the control group(30.0%),and the difference was not significant(P>0.05).(4) During the treatment, no obvious adverse reaction occurred in the two groups.Conclusion The analgesic efficacy of methylene blue mixture combined with Hemorrhoid Fistula Detoxification Lotion is satisfactory for the treatment of mixed hemorrhoid patients after Milligant-morgant hemorrhoidectomy,having low incidence of urinary retention after the operation and being safe and effective.