综合性护理干预对恶性淋巴瘤患者化疗后癌因性疲乏、遵医嘱行为和疗效的影响

The effect of comprehensive nursing intervention on the doctor's order behavior and curative effect of cancer fatigue in patients with malignant lymphoma after chemotherapy

目的探讨综合性护理干预对恶性淋巴瘤患者化疗后癌因性疲乏、遵医嘱行为和疗效的影响。方法选取恶性淋巴瘤患者72例,按随机双盲法分为干预组37例和对照组35例。两组患者均接受常规化疗治疗,化疗期间,对照组患者给予常规护理干预,干预组患者在常规护理的基础上给予综合性护理干预。经不同护理干预后,比较两组患者心理状态、癌因性疲乏程度、遵医嘱行为依从情况及临床治疗效果。结果干预前,两组患者SAS、SDS评分比较差异无统计学意义(P>0.05);干预后,两组患者SAS、SDS评分较干预前均明显降低,且干预组SAS、SDS评分明显低于对照组(P<0.05)。干预前,两组患者癌因性疲乏(无疲乏、轻度疲乏、中度疲乏、重度疲乏)程度比较差异无统计学意义(P>0.05);干预后,两组患者癌因性疲乏程度较干预前明显改善,且干预组癌因性疲乏程度改善明显优于对照组(P<0.05)。干预后,干预组遵医嘱行为(遵医嘱用药、合理饮食、适当运动)依从情况明显优于对照组,差异有统计学意义(P<0.05);干预后,干预组总有效率明显高于对照组,差异有统计学意义(P<0.05)。结论综合性护理干预应用于恶性淋巴瘤化疗治疗期间,可明显消除患者不良心理,改善其癌因性疲乏症状,提高其遵医嘱行为及临床疗效。

Objective To explore the effect of comprehensive nursing intervention on the doctor's order behavior and curative effect of cancer fatigue in patients with malignant lymphoma after chemotherapy. Methods A total of 72 patients with malignant lymphoma were selected. According to the double-blind method, they were randomly divided into the intervention group with 37 cases and the control group with 35 cases.Patients in two groups were treated with conventional chemotherapy.During chemotherapy, patients in the control group were given conventional nursing intervention, while those in the intervention group were given comprehensive nursing intervention on the basis of conventional nursing.After different nursing interventions, the psychological state, degree of cancer-induced fatigue, compliance with medical advice and clinical treatment in the two groups were compared. Results Before intervention, there were no statistically significant differences in Self-rating Anxiety Scale (SAS) score, Self-rating Depression Scale(SDS)score between the two groups(P>0.05). After the intervention, SAS and SDS scores of the two groups were significantly lower than before the intervention, and the SAS and SDS scores in the intervention group were significantly lower than those of the control group(P<0.05). Before the intervention, there was no statistically significant difference in the degree of cancer-induced fatigue (no fatigue, mild fatigue, moderate fatigue, severe fatigue) between the two groups(P>0.05). After the intervention, the degree of cancer-induced fatigue in the two groups was significantly improved compared with that before the intervention, and the degree of cancer-induced fatigue in the intervention group was significantly better than that in the control group between the two groups(P<0.05). After the intervention, the compliance of the intervention group with the prescribed behavior (prescribed medication, reasonable diet and appropriate exercise) was significantly better than that of the control group, and the difference was statistically significant (P<0.05). After the intervention, the total effective rate of the intervention group was significantly higher than that of the control group, and the difference was statistically significant(P<0.05). Conclusions Comprehensive nursing intervention applied in malignant lymphoma chemotherapy treatment periodcan significantly eliminate the adverse psychological patients, improve their cancer-induced fatigue symptoms, improve their compliance with the doctor's advice behavior and clinical efficacy.