不同类型老年乙型肝炎患者的HBV-DNA、HBsAg定量检测结果

The Results of Quantitative Detection of HBV-DNA、HBsAg in Different Types of Elderly Patients with Hepatitis B

目的探讨HBV-DNA、HBsAg定量检测在不同类型老年乙型肝炎患者诊治中的应用价值。方法选取2013年7月至2018年7月医院收治的老年慢性乙型肝炎患者80例作为试验组;选取同期的老年乙型肝炎肝硬化患者80例作为对照组。对两组进行HBV-DNA和HBsAg定量检测并对比,分析不同类型老年乙型肝炎患者HBV-DNA与HBsAg的特点及其相关性。结果两组的HBsAg与HBV-DNA均成正相关。试验组的HBsAg与HBV-DNA均高于对照组,差异有统计学意义(P<0.05)。结论 HBV-DNA与HBsAg定量检测是体现老年慢性乙型肝炎患者与老年乙型肝炎肝硬化患者病情的基准指标。

Objective To analyse the application value of quantitative detection of HBV-DNA、HBsAg in the diagnosis and treatment of different types of elderly patients with hepatitis B.Methods Confirmed elderly patients with chronic hepatitis B accepted in our hospital from July 2013 to July 2018(total 80 cases),and let elderly patients with hepatitis B cirrhosis(total 80 cases)as the control group.Through quantitative detection and comparison of HBV-DNA and HBsAg,to discuss the characteristics and correlation of HBV-DNA and HBsAg in different types of elderly patient with hepatitis B.Results The level of HBsAg was positively correlated with the level of HBV-DNA in the two groups.Furthermore,the HBsAg level and the quantitative level of HBV-DNA in the experimental group were higher than that in the control group.The testing data was with the differences statistically significant(P<0.05).Conclusion The quantitative detection of HBV-DNA、HBsAg is a benchmark indicator reflecting the condition of elderly patients with chronic hepatitis B and elderly patients with hepatitis B cirrhosis.