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吉西他滨单药与吉西他滨联合化疗用于晚期胰腺癌中的临床价值 被引量:4

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摘要 目的分析吉西他滨单药与吉西他滨联合化疗用于晚期胰腺癌中的临床价值。方法 38例晚期胰腺癌患者作为研究对象,依据入院先后顺序分成对照组和观察组,各19例。对照组患者采用吉西他滨单药化疗,观察组患者采用吉西他滨联合化疗。对比两组患者化疗效果、1年生存情况及化疗不良反应发生情况。结果观察组患者化疗总有效率为73.7%、1年生存率为57.9%;对照组患者化疗总有效率为42.1%、1年生存率为26.3%。观察组患者化疗总有效率及1年生存率均高于对照组,差异均具有统计学意义(P<0.05)。对照组患者化疗不良反应发生率为31.6%,观察组患者化疗不良反应发生率为63.2%。观察组患者化疗不良反应发生率略高于对照组,但差异无统计学意义(P>0.05)。结论对晚期胰腺癌患者采用吉西他滨联合化疗方案进行治疗,可有效提高临床化疗效果及患者生存率,且不增加化疗不良反应,值得临床推广。
作者 董海鹏
出处 《中国现代药物应用》 2019年第9期114-115,共2页 Chinese Journal of Modern Drug Application
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