孕晚期胎儿胆囊的磁共振监测指标研究

Study on magnetic resonance monitoring index of fetal gallbladder during lategestation

目的测量妊娠28~35周胎儿胆囊的磁共振正常值,并观察胎儿胆囊的生长发育情况,为产前检查评价胎儿胆囊发育提供新的检测方法。方法选取大连市妇女儿童医疗中心2017年6月至2018年5月行胎儿腹部磁共振检查的单胎孕妇100例,将孕妇按孕龄分为两组:A组妊娠28~31周,64例;B组妊娠32~35周,36例。记录磁共振测量的胎儿胆囊长度、宽度、横径,计算胆囊体积。结果A组磁共振胆囊未显示1例,示胎儿双胆囊1例,出生后复查均正常。胆囊显示率A组为98.4%(63/64),B组为100.0%(36/36);异常率A组为3.1%(2/64),B组为0。B组胆囊长度、宽度、橫径和体积均明显大于A组[(16.5±6.0)mm比(13.2±4.2)mm、(6.5±3.5)mm比(5.2±1.1)mm、(6.8±2.6)mm比(6.4±3.4)mm和(373.3±284.1)mm^3比(258.5±232.4)mm^3],差异有统计学意义(P<0.05)。结论孕晚期胎儿磁共振检查是产前评价胎儿生长发育的新手段,有临床应用价值。

Objective To explore the normal reference range of fetal gallbladder in 28 to 35 weeks of pregnancy under magnetic resonance imaging characteristics, observe and explore the growth and development of fetal gallbladder, and provide a new detection method for evaluating fetal growth and development for prenatal examination. Methods One hundred single pregnant women who had underwent fetal abdominal magnetic resonance imaging from June 2017 to May 2018 in Dalian Municipal Women and Children′s Medical Center were selected. The pregnant women were divided into 2 groups according to the gestational weeks: group A (pregnancy 28 to 31 weeks, 64 cases) and group B (pregnancy 32 to 35 weeks, 36 cases). The length, width and transverse diameter of fetal gallbladder were measured by magnetic resonance, and the gallbladder volume was calculated. Results In group A, magnetic resonance result showed that 1 case had no gallbladder and 1 case had double gallbladder, but the fetal gallbladders of these 2 cases were normal after birth. The display rate of fetal gallbladder in group A was 98.4%(63/64), and that in group B was 100.0%(36/36);the abnormal rate in group A was 3.1%(2/64), and that in group B was 0. The length, width, transverse diameter and volume of gallbladder in group B were significantly higher than those in group A:(16.5 ± 6.0) mm vs.(13.2 ± 4.2) mm,(6.5 ± 3.5) mm vs.(5.2 ± 1.1) mm,(6.8 ± 2.6) mm vs.(6.4 ± 3.4) mm and (373.3 ± 284.1) mm^3 vs.(258.5 ± 232.4) mm^3, and there were statistical differences (P<0.05). Conclusions Fetal magnetic resonance during lategestation has the new means of prenatal evaluation of fetal growth and development, which has clinical application value.