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术前新辅助化疗(NACT)联合手术治疗Ⅰb2和Ⅱa期宫颈癌的疗效及不良反应探讨 被引量:4

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摘要 目的研究探讨术前新辅助化疗(NACT)联合手术治疗Ⅰb2和Ⅱa期宫颈癌的疗效及不良反应。方法选取我院自2016年10月~2018年10月接受治疗的60例Ⅰb2和Ⅱa期宫颈癌患者作为本次的研究对象,采用随机数字表法将其分为两组,对照组患者采用腹腔镜宫颈癌根治术治疗,实验组患者采用术前新辅助化疗联合腹腔镜宫颈癌根治术治疗,对比两组患者的临床有效率、不良反应、手术时间和肛门排气时间。结果实验组患者的临床有效率是90.00%,比对照组高10.00%,手术时间比对照组时间短,两组数据比较有统计学意义,P<0.05,化疗后胃肠道反应发生率为90.00%,骨髓抑制的发生率为40.00%,对症治疗后对手术均无影响。肛门排气时间比对照组低,但P>0.05。结论对Ⅰb2和Ⅱa期宫颈癌患者实施术前新辅助化疗可以缩小病灶,有利于腹腔镜宫颈癌根治术的实施,缩短手术时间,值得在临床上推广应用。
作者 王静 金志军
出处 《实用妇科内分泌电子杂志》 2019年第11期117-117,127,共2页 Electronic Journal of Practical Gynecological Endocrinology
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