DNA步行者分子机器研究新进展

Recent research progress on DNA walker-based molecular machines

作为人类向大自然学习过程中迈出的重要一步,人工分子机器的研究越来越受到人们的重视.由于具有碱基配对的精确性、序列的可编程性、二级结构的多样性和可控性等一系列优势, DNA被认为是最有前途的一类分子机器构筑材料之一.本综述依据驱动力的不同,对一类重要的分子机器——DNA步行者分子机器的最新研究进展进行了介绍,并对该类分子机器的未来发展进行了展望.

As an important step in learning from nature, artificial molecular machines have attracted more and more public attention. Due to the distinct advantages of well-defined Watson-Crick base pairing rule, programmable sequence,diverse and controllable secondary structures, DNA are considered as promising building blocks for artificial molecular machines. In this review, recent research progress on DNA walker, an important member in artificial molecular machine family, is introduced on the basis of difference in driving forces, and the future development of this kind of molecular machines is prospected.