局灶性机化性肺炎误诊为肺癌一例并文献复习

Focal organizing pneumoniamimics lung cancer one case report and literature review

目的提高对局灶性机化性肺炎(FOP)的认识和诊断水平。方法报道1例FOP的临床表现、诊治经过以及转归。以"局灶性机化性肺炎[关键词]"且"孤立性肺结节[摘要]"为检索式检索中国知网;以"Focal Organizing Pneumonia[Title/Abstract]"为检索式检索PubMed数据库,检索时间截至2018年10月。结果患者男,61岁,体检胸部CT发现右肺上叶恶性形态特征的孤立性结节,术后病理证实为FOP。PubMed、中国知网数据库共检索到21篇FOP相关文献,共161例患者。其中男119例,女42例;年龄范围为29~80岁;临床症状以咳嗽、咳痰、胸痛、发热及呼吸困难为主。仅10例未行手术治疗,其余均拟诊为肺癌行手术治疗。结论胸部CT表现为分叶、毛刺等孤立型恶性形态特征病变时,应考虑FOP的可能,完善各种检查以除外良性病变,避免不必要的手术创伤。

The clinical manifestation, diagnosis, treatment course and outcome of 1 case of FOP were reported." Focal Organizing Pneumonia [Key Words]" and " Isolated Pulmonary Nodules [Abstract]" were used as retrieval methods to search CNKI." Focal Organizing Pneumonia [Title/Abstract]" was retrieved in the PubMed database as of October 2018. Results A 61-year-old male presented with solitary nodules with malignant morphological features in the upper lobe of the right lung on chest CT.PubMed and CNKI databases retrieved a total of 21 articles related to FOP, including 161 patients.There were 119 males and 42 females.The age range is 29-80 years old;The main clinical symptoms were cough, sputum, chest pain, fever and dyspnea.Only 10 cases did not receive surgical treatment, and the rest were planned to receive surgical treatment as lung cancer. Conclusions The possibility of FOP should be considered when the lung CT shows isolated malignant morphological characteristics such as lobulation and burrs.The essential examinations should be completed to exclude benign lesions and avoid unnecessary surgical trauma.