摘要
糖尿病是一种常见的慢性代谢性疾病,已成为继恶性肿瘤和心脑血管疾病之后的第三大疾病,其中Ⅱ型糖尿病发病最为普遍,其发病机制目前尚不明确。原花青素是一种来源广泛、安全度高、生物活性优良的天然植物化学物,具有良好的抗糖尿病作用。本文系统综述了原花青素对Ⅱ型糖尿病防治作用的研究进展及潜在的作用机制。
Diabetes mellitus, one of the most common chronic metabolic diseases, has become the third major disease after malignant tumor and cardiovascular and cerebrovascular diseases. Type Ⅱ diabetes mellitus (T2DM) is the most prevalent form of diabetes. However, the pathogenesis of T2DM is still unclear so far. Procyanidins, a group of natural phytochemicals with a wide range of sources, high safety and good biological activity, can exert antidiabetic effect. The potential mechanism of action of procyanidins in the prevention and control of T2DM is systematically reviewed in this article.
作者
刘丹
邓建军
张超
张敬华
杨海霞
LIU Dan;DENG Jianjun;ZHANG Chao;ZHANG Jinghua;YANG Haixia(College of Public Health, Health Science Center, Xi’an Jiaotong University, Xi’an 710061,China;School of Chemical Engineering, Northwest University, Xi’an 710069,China)
出处
《食品科学》
EI
CAS
CSCD
北大核心
2019年第9期302-308,共7页
Food Science
基金
国家自然科学基金面上项目(21676212)
