银川市1001例育龄妇女B群链球菌检测及耐药性分析

Detection and Drug Resistance Analysis of Group B Streptococcus in 1001 Women of Childbearing Age in Yinchuan City

目的分析银川市1001例育龄妇女阴道和直肠中B群链球菌的检出情况及抗菌药物耐药性。方法对18～45岁1001例妇女阴道和直肠标本进行病原菌培养,对检出的B群链球菌用珠海美华鉴定系统进行药物敏感性试验。结果 1001例妇女阴道及直肠标本中共培养B群链球菌51株,检出率为5.09%。18岁～组妇女B群链球菌检出率均低于30岁～和40～45岁组妇女,30岁～组妇女B群链球菌检出率低于40～45岁妇女(P均<0.05)。51株B群链球菌对万古霉素、青霉素类、碳青霉烯类、利奈唑胺的耐药率均为0,对红霉素类耐药率均达到80%以上。结论 B群链球菌对青霉素类、糖肽类、碳青霉烯类抗生素耐药率较低,对红霉素类抗生素耐药率较高。

Objective To analyze the detection result and drug resistance of group B streptococcus(GBS)in vagina and rectum of women of childbearing age in Yinchuan.Methods Pathogenic bacteria were cultured in 1001 vaginal and rectal specimens of women aged 18-45 years.Drug susceptibility test of group B streptococcus was carried out by Zhuhai meihua identification system.Results A total of 51 strains of group B Streptococcus were cultured in 1001 women's vaginal and rectal specimens,the detection rate was 5.1%.The detection rate of group B Streptococcus in 18-years old and 40-45 years old women was lower than that in 30-years old and 40-45 years old women(P<0.05).The resistance rates of 51 strains of group B Streptococcus to vancomycin,penicillins,carbapenems and linezolid were all 0,and to erythromycin were more than 80%.Conclusion The resistance rate of group B streptococcus to penicillins,glycopeptides and carbapenems was lower,while the resistance rate to erythromycins was higher.