男性幽门螺旋杆菌感染与骨质相关关系研究

Correlation between Helicobacter pylori infection and bone in men

目的 了解目前沈阳地区男性幽门螺旋杆菌感染情况及骨质相关指标,并分析其相关性。方法 收集本体检中心检测幽门螺旋杆菌,同时检测骨密度检测及维生素D、碱性磷酸酶等相关指标的人群的临床资料。将研究对象分为幽门螺旋杆菌阴性组和幽门螺旋杆菌阳性组,分析幽门螺旋杆菌感染和骨密度检测及维生素D、碱性磷酸酶等相关指标的相关关系。结果 443例男性检测幽门螺旋杆菌者中,阳性检出率为32.05%。2组骨密度、维生素D比较,差异有统计学意义(P<0.05);2组碱性磷酸酶比较差异无统计学意义(P>0.05)。结论 幽门螺旋杆菌阳性感染可能与骨密度及维生素D有关,而不能认为与碱性磷酸酶之间存在关系。

Objective To investigate the status of Helicobacter pylori infection and bone-related indicators in men and their correlation. Methods A data of patients performed examination of Helicobacter pylori, and bone related indexes such as vitamin D and alkaline phosphatase in our physical examination center were retrospectively analyzed. The subjects were divided into Helicobacter pylori -negative group and Helicobacter pylori -positive group. The correlation between Hp infection and bone mineral density, vitamin D, alkaline phosphatase were analyzed. Results Out of 443 males tested for Helicobacter pylori , the positive detection rate was 32.05%. There were significant differences in bone mineral density and vitamin D between the two groups ( P <0.05), but no significant difference in alkaline phosphatase ( P >0.05). Conclusion The Hp infection may be related to bone density and vitamin D, but it can not be considered to be related to alkaline phosphatase.