老年B细胞淋巴瘤诊断及预后评估研究

Diagnosis and Prognostic Evaluation of Elderly B-cell Lymphoma

B细胞淋巴瘤是常见的淋巴瘤类型,发病年龄逐年上升,老年患者发病率不断增加。老年患者具有独特的病理特点和临床表现,对有创检查耐受性差,影响其预后。随着科学技术手段的不断进步,在新仪器、新技术的帮助下,老年B细胞淋巴瘤患者的影像诊断更加全面,病理诊断逐渐由宏观向分子和基因方向发展,预后评估手段不断更新发展。对老年B细胞淋巴瘤诊断及预后评估发展现状进行了简要综述。

B-cell lymphoma is the most common pathological subtype of lymphoma with an increasing age of onset,among which elderly patients have became the leading population in this disease. Elderly B-cell lymphoma patients are characterized by specific clinical and pathological features,as well as having poor tolerance of invasive inspection,leading to inferior prognosis. With the continuous improvement of scientific technology,new instruments and new techniques emerge in diagnosis and prognostic evaluation of lymphoma. The imaging diagnosis of elderly B-cell lymphoma patients is more comprehensive,the pathological diagnosis is gradually developed towards molecular and genetic direction from macroscopic view,and the prognostic evaluation method is constantly updated. This paper reviews the development of diagnosis and prognostic evaluation in B-cell lymphoma.