温针灸联合三维牵引治疗腰椎间盘突出症急性期的疗效及对IL-1β、IL-6、hs-CRP的影响

Effects of Warm Needle Moxibustion Combined with Three-dimensional Traction on Acute Lumbar Disc Herniation and IL-1β,IL-6,hs-CRP

目的观察温针灸联合三维牵引治疗急性腰椎间盘突出症的临床疗效并探讨其作用机制。方法 148例患者随机分为治疗组和对照组各74例。对照组给予基础治疗和三维牵引,治疗组加用温针灸法,治疗10 d为1个疗程,共治疗2个疗程。比较两组的临床疗效、疼痛视觉模拟评分法评分(VAS)、日本骨科协会下腰痛功能评价表评分(JOA)和血清白细胞介素-1β(IL-1β)、白细胞介素-6(IL-6)、超敏C反应蛋白(hs-CRP)水平。结果治疗组的总有效率97.30%高于对照组的89.19%(P <0.05);治疗后两组VAS评分和血清IL-1β、IL-6、hs-CRP水平均下降(均P <0.05),治疗第10日和20日时,治疗组的VAS评分和IL-1β、IL-6、hs-CRP水平均低于对照组(均P <0.05);两组JOA评分和直腿抬高试验评分均升高(均P <0.05),治疗第10日和20日时,治疗组的JOA评分和直腿抬高试验评分均高于对照组(均P <0.05)。结论温针灸法联合三维牵引治疗急性腰椎间盘突出症可以通过抑制炎症因子表达,从而缓解疼痛,提高临床疗效。

Objective: To observe the effects of warm needle moxibustion combined with three-dimensional traction on acute lumbar disc herniation. Methods: 148 patients were randomly divided into the treatment group and the control groups. The control group was given basic treatment and three-dimensional traction,and the treatment group was treated with warm acupuncture for 20 days. The following data was analyzed and compared: the clinical efficacy,VAS,JOA and the levels of serum IL-1β,IL-6 and hs-CRP. Results: The total effective rate of the treatment group was 97.30%,higher than 89.19% of the control group(P < 0.05). After treatment,the VAS scores and serum levels of IL-1β,IL-6 and hs-CRP in both groups decreased(all P < 0.05). On the 10th and 20th days,those of the treatment group were lower than those of the control group(all P < 0.05). JOA scores and straight leg elevation test scores increased in both groups(P < 0.05). On the 10th and 20th days,those of the treatment group were higher than those of the control group(all P < 0.05). Conclusion: Warm needle moxibustion combined with three-dimensional traction on acute lumbar disc herniation can relieve pain and improve clinical efficacy by inhibiting the expression of inflammatory factors.