保乳术与改良根治术在早期乳腺癌治疗中的效果对比分析

A Comparative Analysis of the Effect of Breast Conserving Surgery and Modified Radical Mastectomy in the Treatment of Early Breast Cancer

目的 分析保乳手术和改良根治术治疗早期乳腺癌的临床疗效。方法 回顾性分析该院中2016年4月—2018年6月间收入的所有早期乳腺癌患者的一般资料,根据该次实验要求抽取出其中62例患者纳入该次研究开展实验,通过双色球分组法,将所有患者均分两组红色球为对照组,蓝色球为实验组,每组中录入31例患者开展研究。给予对照组患者实行改良根治术,实验组患者实行保乳手术。根据两组患者的并发症发生情况、转移率以及复发率等情况进行对比,同时记录所有患者的手术时间、术中出血量、术后乳房美观度评分,对比两组患者的手术治疗效果。结果 该次研究成果显示,对照组中共4例转移(12.90%),2例局部复发(6.45%),共11例出现并发症(35.48%),而实验组中仅1例出现并发症(3.23%)(χ~2=33.316 5,P=0.0000),2例局部复发(6.45%)(χ~2=0.000 0,P=1.000 0),1例转移(3.23%)(χ~2=6.305 8,P=0.012 03),转移率与并发症数据差异具有统计学意义。同时实验结果显示,实验组患者的各项手术指标较对照组来说明显更优,数据对比分析差异明显(P=0.0000)。结论较改良根治术来说,保乳手术能够更为有效的对患者的病症进行治疗,降低患者的并发症发生和转移状况是一种有效且安全的手术方案,能够有效改善患者的治疗效果,值得在临床上推广使用。

Objective To analyze the clinical efficacy of breast conserving surgery and modified radical mastectomy in the treatment of early breast cancer. Methods The general data of all early breast cancer patients in our hospital from April 2016 to June 2018 were retrospectively analyzed. According to the requirements of this experiment, 62 patients were selected and included in this study. All patients were divided into two groups, red ball as control group and blue ball as experimental group. 31 patients in each group were enrolled in the study. The patients in the control group were treated with modified radical mastectomy and the patients in the experimental group were treated with breast conserving surgery. The occurrence of complications, metastasis rate and recurrence rate of the two groups were compared;the operation time, intraoperative bleeding volume and postoperative breast esthetic score of all patients were recorded, and the surgical effect of the two groups was also compared. Results The results of this study showed that there were 4 cases of metastasis (12.90%), 2 cases of local recurrence (6.45%) and 11 cases of complications (35.48%) in the control group, while only 1 case of complications (3.23%) in the experimental group (χ^2=33.316 5,P=0.000 0), 2 cases of local recurrence (6.45%)(χ^2=0.000 0,P=1.000 0), 1 case of metastasis (3.23%)(χ^2=6.305 8,P=0.012 03). There was a statistically significant difference in metastasis rate and complication data between the two groups. At the same time, the experimental results showed that the surgical indicators of the experimental group were significantly better than those of the control group, and the data were significantly different (P=0.0000). Conclusion Compared with modified radical mastectomy, breast-conserving surgery is more effective in the treatment of patients' symptoms, reducing the occurrence and metastasis of complications, which is an effective and safe surgical program. It can effectively improve the treatment effect of patients, and is worth promoting in clinical use.