光声成像技术在早期肝癌诊断和治疗中的应用

Application of PAI in the diagnosis and treatment of early liver cancer

光声成像技术具有光学成像高分辨率和超声成像高穿透深度的优点,能同时获取生物组织结构信息与分子、细胞和血氧饱和度等功能信息,可提供活体深层组织高分辨率的医学影像。近年来,光声成像技术在肝脏恶性肿瘤诊断与治疗中的应用逐渐受到重视,新的成像系统陆续出现,各种纳米探针在手术导航的精确度越来越高,随着技术的进步,更多边界界定及探针技术将会涌现。本文将对光声成像原理、光声成像系统进行介绍,并概括光声成像系统在肝癌临床治疗过程中的广泛应用,有助于临床对肝脏肿瘤的早期诊断和精准治疗。

Photoacoustic imaging (PAI) is a kind of nondestructive biomedical imaging technology.It provides deeper tissue imaging with high spatial resolution along with functional imaging.Recently,PAI technology has developed significantly in early diagnosis and accurate boundary recognition of liver cancer.The new imaging system are emerging,and various nanoprobes are more accurate in surgical navigation.As PAI technology advances,more boundary demarcation and probe techniques will come to the fore.The principle and imaging system of photoacoustic are introduced in this paper.The wide application of PAI system in clinical treatment of liver cancer is summarized,which are beneficial for early diagnosis and accurate treatment of liver cancer.