摘要
光声成像技术具有光学成像高分辨率和超声成像高穿透深度的优点,能同时获取生物组织结构信息与分子、细胞和血氧饱和度等功能信息,可提供活体深层组织高分辨率的医学影像。近年来,光声成像技术在肝脏恶性肿瘤诊断与治疗中的应用逐渐受到重视,新的成像系统陆续出现,各种纳米探针在手术导航的精确度越来越高,随着技术的进步,更多边界界定及探针技术将会涌现。本文将对光声成像原理、光声成像系统进行介绍,并概括光声成像系统在肝癌临床治疗过程中的广泛应用,有助于临床对肝脏肿瘤的早期诊断和精准治疗。
Photoacoustic imaging (PAI) is a kind of nondestructive biomedical imaging technology.It provides deeper tissue imaging with high spatial resolution along with functional imaging.Recently,PAI technology has developed significantly in early diagnosis and accurate boundary recognition of liver cancer.The new imaging system are emerging,and various nanoprobes are more accurate in surgical navigation.As PAI technology advances,more boundary demarcation and probe techniques will come to the fore.The principle and imaging system of photoacoustic are introduced in this paper.The wide application of PAI system in clinical treatment of liver cancer is summarized,which are beneficial for early diagnosis and accurate treatment of liver cancer.
作者
石磊
田昊
张希恬
龙子宁
黄畅
曾宁
方驰华
SHI Lei;TIAN Hao;ZHANG Xitian;LONG Zining;HUANG Chang;ZENG Ning;FANG Chihua(The Second Clinical Medical College,Southern Medical University;Digital-medicine Clinical Engineering Technology Research Center ofGuangdong,Guangzhou 510282,China)
出处
《分子影像学杂志》
2019年第2期145-150,共6页
Journal of Molecular Imaging
基金
"十二五"国家高技术研究发展(863)计划(2012A A021105)
"十三五"国家重点研发计划数字诊疗装备研发重点专项(2016YFC0106500)
NSFC-广东联合基金项目(U1401254)
国家自然科学基金重大仪器项目(81627805)
广州市科技计划(201604020144)
关键词
光声成像
图像重建
早期肝癌
边界确定
photoacoustic imaging
image reconstruction
early liver cancer
boundary defining