体外反搏治疗急性重症病毒性脑炎的临床疗效观察

Clinical Efficacy of External Counterpulsation in the Treatment of Acute Severe Viral Encephalitis in Children

目的:探讨以体外反搏为主的康复手段治疗急性重症病毒性脑炎的临床疗效。方法:选择2015年6月～2016年6月在我院康复科就诊的42例急性重症病毒性脑炎患儿,按照家长治疗意愿分成治疗组和对照组,每组21例。治疗一个月和三个月后,分析和比较两组的治疗前后粗大运动功能评定量表(GMFM)、平衡功能测量(Berg量表)和修订的Glasgow意识障碍评分量表评分的变化。结果:两组患儿平衡能力总有效率(显效率与有效率之和)分别为85.7%和57.1%,以及95.2%和66.7%,治疗组疗效明显优于对照组(P<0.05)。两组治疗后1、3个月,GMFM、Glasgow意识障碍评分均较治疗前明显提高(P<0.01),且治疗组治疗1、3个月后GMFM显著高于对照组(P<0.01)。结论:以体外反搏为主的早期康复治疗有助于急性重症病毒性脑炎患者促醒及运动功能恢复。

Objective: To explore the clinical effect of rehabilitation treatment on the acute severe viral encephalitis with extracorporeal counterpulsation. Methods: 42 cases of children with acute severe viral encephalitis who were admitted to the rehabilitation department of our hospital from June 2015 to June 2016 were selected and divided into the treatment group and the control group according to the treatment intention, with 21 cases in each group. At one month and three months after treatment, the changes of rating scale(GMFM) gross motor function, balance function measurement(Berg scale) and the revision of the Glasgow consciousness rating scale score changes were compared between two groups before and after treatment. Results: The total effective rate(the sum of apparent efficiency and effective rate) of the both groups were 85.7% and 57.1% respectively, and 95.2% and 66.7% respectively. The therapeutic effect of treatment group was significantly better than that of the control group(P<0.05). At 1 and 3 months after treatment,the GMFM and Glasgow consciousness disorder scores were significantly higher in both groups than those before treatment(P<0.01), and they were significantly higher in the treatment group than those in the control group(P<0.01). Conclusion: Early rehabilitation treatment with extracorporeal counterpulsation was beneficial to the recovery of acute severe viral encephalitis.