电针配合中药熏蒸对慢性前列腺炎患者疗效和前列腺液中IL-17、TNF-α水平的影响

Effects of Electroacupuncture Combined with Traditional Chinese Medicine Fumigation on the Efficacy of Patients with Chronic Prostatitis and Levels of IL-17 and TNF-α in Prostatic Fluid

目的:探讨电针配合中药熏蒸对慢性前列腺炎患者疗效和前列腺液中白细胞介素-17(IL-17)、肿瘤坏死因子-α(TNF-α)水平的影响。方法:选取2017年6月～2018年8月我院接收的慢性前列腺炎患者120例,根据随机数字表法分为观察组(n=60)和对照组(n=60)。对照组采用西医药物治疗,观察组采用电针配合中药熏蒸治疗。评价并比较两组疗效,比较两组患者治疗前后美国国立卫生研究院慢性前列腺炎症状指数(NIH-CPSI)评分、最大尿流率(Qmax)、平均尿流率(Qave)以及前列腺液IL-17、TNF-α水平。结果:观察组总有效率为90.00%,明显高于对照组的71.67%(P<0.05)。治疗后,两组NIH-CPSI评分中的排尿症状、疼痛或不适、生活质量评分以及总分均明显降低,且观察组NIH-CPSI各维度评分及总分均低于对照组(P<0.05)。治疗后,两组Qmax、Qave明显上升,且观察组Qmax、Qave明显高于对照组(P<0.05)。治疗后,两组前列腺液IL-17、TNF-α水平明显降低,且与对照组比较,观察组IL-17、TNF-α水平明显更低(P<0.05)。结论:电针配合中药熏蒸治疗慢性前列腺炎疗效确切,其能明显改善患者病情和尿流率,降低患者前列腺液中IL-17、TNF-α水平。

Objective: To investigate the effects of electroacupuncture combined with traditional Chinese medicine fumigation on the efficacy of patients with chronic prostatitis and levels of interleukin-17(IL-17) and tumor necrosis factor-α(TNF-α) in prostatic fluid.Methods: 120 patients with chronic prostatitis who were admitted to our hospital from June 2017 to August 2018 were selected, and they were divided into observation group(n=60) and control group(n=60) according to the random number table method. The control group was treated with western medicine, and the observation group was treated with electroacupuncture combined with traditional Chinese medicine fumigation. The curative effects of the two groups were evaluated and compared. The NIH-CPSI score, maximal urinary flow rate(Qmax), mean urinary flow rate(Qave) and the levels of IL-17 and TNF-α in prostatic fluid were compared between the two groups before and after treatment. Results: The total effective rate of the observation group was 90.00%, which was significantly higher than71.67% of the control group(P <0.05). After treatment, the urinary symptoms, pain or discomfort, quality of life and total score in NIH-CPSI scores in both groups were significantly lower, and the NIH-CPSI dimensions score and total scores in the observation group were lower than those in the control group(P<0.05). After treatment, Qmax and Qave in both groups were significantly increased, and Qmax and Qave in observation group were significantly higher than those in control group(P<0.05). After treatment, the levels of IL-17 and TNF-α in prostatic fluid of the two groups were significantly decreased, and compared with the control group, the levels of IL-17 and TNF-α were significantly lower in the observation group(P<0.05). Conclusion: Electroacupuncture combined with traditional Chinese medicine fumigation is effective in the treatment of chronic prostatitis, which can significantly improve the patient’s condition and urine flow rate, while reducing the IL-17, TNF-α levels in prostatic fluid.