低分割放疗治疗颈部血管瘤的疗效观察

Observation on the efficacy of hypofractionated radiotherapy in the treatment of cervical hemangioma

目的:分析低分割放射治疗对颈部血管瘤的疗效。方法:回顾性分析我院7例颈部血管瘤患者,其中颈动脉体瘤患者2例,颈静脉球瘤患者5例,采用低分割放射治疗,肿瘤剂量DT 55 Gy(BED:82.5 Gy)/11 f,随访26～48个月。结果:采用低分割三维适形放疗后患者瘤体缩小明显,放疗前后肿瘤大小比较差异有统计学意义(P<0.05);其中缓解明显6例,随访期间未复发,总有效率85.7%;放疗前后患者生活质量评分比较差异有统计学意义(P<0.05)。结论:放射治疗是无法手术或不愿手术颈部血管瘤患者的首选治疗方法,低分割放疗可使肿瘤明显缩小,缩短治疗时间,迅速改善患者临床症状,提高生活质量,肿瘤复发率低,长期疗效显著。

Objective:To observe the clinical effect of hypofractionated radiotherapy to carotid body tumor and glomus jugulare tumor.Methods:There were 7 patients with cervical hemangioma,in which 2 patients were tumor of carotid body and 5 patients were tumor of glomus jugulare.All of them adopted hypofractionated radiotherapy,dose of radiotherapy for tumor 55 Gy(BED:82.5)/11 faction,follow-up 26~48 months.Results:There was significant difference to compare the size of tumor before and after radiotherapy(P<0.05),6 cases had obvious effect,no recurrence during the follow-up period.The effective rate was 85.7%.There was significant difference to compare the quality of life before and after radiotherapy(P<0.05).Conclusion:Radiotherapy is perferred treatment with cervical hemangioma patients who are unwilingness or inability to operate.Hypofractionated radiotherapy makes the tumor significantly reduced,improves clinical symptoms,and the quality of life.Long-term curative effect is remarkable.