女宝胶囊气相特征图谱

Specific Chromatogram of Nvbao Capsules by GC

目的:利用气相色谱法建立女宝胶囊特征图谱的质量评价方法。方法:采用气相色谱;DB-FFAP毛细管柱(柱长为30 m,内径为0.25 mm,膜厚度为0.25μm);程序升温:初始温度为100℃,保持15 min,以8℃·min^(-1)的速率升温至220℃,保持30 min;进样口温度为240℃;检测器温度为260℃;载气为氮气,流速为1.0 mL·min^(-1)。结果:建立的特征图谱信息丰富,6味含有挥发油类中药材中的16个特征峰分离良好,且重复性和稳定性的RSD均小于1.0%。结论:本研究所建立的方法快速、可靠,且专属性强,适用于全面控制女宝胶囊的质量。

Objective: To establish a specific GC method for quality evaluation of Nvbao Capsules. Methods: GC with DB-FFAP quartz capillary (Length 30 m,inner diameter 0.25 mm,membrane thickness 0.25 μm )was adopted in this study.The GC conditions were set as follows:the initial temperature of 100 ℃ was maintained for 15 minutes,raised to 220 ℃ with the heating rate of 8 ℃· min -1 maintained for 30 minutes.The temperature of inlet and detector were set at 240 ℃ and 260 ℃,respectively.Nitrogen was used as the carrier gas at the flow rate of 1.0 mL · min -1 . Results: The information of specific chromatogram was abundant,16 characteristic peaks belong to 6 kinds of medicinal materials rich in volatile oil were separated well,and RSD of repeatability and stability were less than 1.0%. Conclusion: The method is fast,simple and reliable,which can be used for the comprehensive quality control of Nvbao Capsules.