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用两种药物对接受人工全膝关节置换术后的老年患者进行静脉自控镇痛的效果探讨 被引量:2

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摘要 目的:研究用右美托咪定联合舒芬太尼对接受人工全膝关节置换术后的老年患者进行静脉自控镇痛的效果。方法:选择在阜宁县人民医院接受人工全膝关节置换术的190例老年患者作为研究对象。将这些患者随机分舒芬太尼组(SF组,n=95)与联合用药组(DC组,n=95)。术后,用舒芬太尼对SF组患者进行静脉自控镇痛,用右美托咪定联合舒芬太尼对DC组患者进行静脉自控镇痛,然后比较两组患者术后不同时间点的VAS评分、Ramsay镇静评分及其不良反应的发生率。结果:术后8h、12h及24h,DC组患者的VAS评分均低于SF组患者,其Ramsay镇静评分均高于SF组患者,P <0.05。在术后镇痛期间,两组患者不良反应的发生率相比,P>0.05。结论:用右美托咪定联合舒芬太尼对接受人工全膝关节置换术后的老年患者进行静脉自控镇痛可取得良好的效果,且用药的安全性较高。
作者 孙红艳
出处 《当代医药论丛》 2019年第6期66-67,共2页
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  • 1李金彪.腰-硬联合麻醉在超高龄患者髋关节置换术中的应用[J].临床麻醉学杂志,2006,22(9):716-716. 被引量:59
  • 2吴新民,岳云,张利萍,王俊科,艾登滨,于布为,薛张纲,黄文起.术后镇痛中帕瑞昔布钠对吗啡用量的节俭作用和安全性—前瞻性、多中心、随机、双盲、安慰剂对照、平行分组研究[J].中华麻醉学杂志,2007,27(1):7-10. 被引量:367
  • 3Mohamed AM. Makki D, Gibbs J, et al. Effect of surgical approach on the early outcome of total hip replacement for femoral neck fractures. Acta Orthop Belg , 2013, 79(6) :667- 671.
  • 4Shapiro A, Zohar E. Zaslansky R, et al. The frequency and timing of respiratory depression in 1524 postoperative patients treated with systemic or neuraxial morphine. J Clin Anesth, 2005,7(7) :537-542.
  • 5Niesters M. Dahan A. Pharmacokinetic and pharmacodynamic considerations for NMDA receptor antagonists in the treatment of chronic neuropathic pain. Expert Opin Drug Metab Toxicol, 2012,8(11):1409-1417.
  • 6Feenstra P. Brunsteiner M. Khinast J, Prediction of drugpackaging interactions via molecular dynamics (MD) simulations. Int J Pharm, 2012.431(1-2) :26-32.
  • 7Gulcin Ural S, Yener 0, Sahin H. et al. The comparison of analgesic effects of various administration methods of diclofenac sodium, transdermal , oral and intramuscular. in early postoperative period in laparoscopic cholecystectomy operations. Pak J Med Sci, 2014,300): 96-100.
  • 8Rivard C, Dickson EL. Vogel RI. et al. The effect of anesthesia choice on post-operative outcomes in women undergoing exploratory laparotomy for a suspected gynecologic malignancy. Gynecol Oncol , 2014.2(26): 90-98.
  • 9Lvovschi V, Arnaud L, Parizot C, et al. Cytokine profiles in sepsis have limited relevance for stratifying patients in the emergency department: a prospective observational study. PLoS One. 2011.6(2) :e28870.
  • 10Hatakeyama N, Matsuda N. Mechanisms of inflammatory response and organ dysfunction: organ-protective strategy by anesthetics. Curr Pharm Des. 2014.10): 80-82.

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