早发型重度子痫前期合并胎儿生长受限期待治疗妊娠结局的相关研究

Pregnancy outcome of early-onset severe pre-eclampsia with fetal growth restriction after expectant treatment

目的研究早发型重度子痫前期合并胎儿生长受限期待治疗的妊娠结局。方法选取2015年12月~2017年10月我院收治的早发型重度子痫前期患者84例作为研究病例,其中合并胎儿生长受限41例(研究组),未合并胎儿生长受限43例(对照组),对两组的临床资料进行回顾性分析,比较两组的母婴结局。结果研究组早产率(31.71%)低于对照组(55.81%),终止妊娠时间(37.13±1.02)周长于对照组(33.21±1.01)周;剖宫产率(92.68%)高于对照组(74.42%),差异有统计学意义(P<0.05),研究组新生儿窒息率、心脏发育不全率、新生儿贫血率、新生儿死亡率以及肺透明膜病变发生率显著低于对照组,差异有统计学意义(P<0.05)。结论对早发型重度子痫前期合并胎儿生长受限的孕产妇实施期待治疗不会增加并发症的发病率,值得应用。

Objective To study the pregnancy outcome of early-onset severe pre-eclampsia with fetal growth restriction after expectant treatment. Methods 84 cases of early-onset severe pre-eclampsia patients admitted to our hospital from December 2015 to October 2017 were selected as study cases, including 41 cases with fetal growth restriction(study group) and 43 cases without fetal growth restriction(control group). The clinical data of the two groups were retrospectively analyzed, and the maternal and infant outcomes of the two groups were compared. Results The early labor rate of the study group(31.71%) was lower than that of the control group(55.81%), and the termination time(37.13±1.02) weeks was longer than that of the control group(33.21±1.01) weeks. The cesarean section rate (92.68%) was higher than that of the control group(74.42%). The differences were statistically significant(P<0.05). The study group's neonatal asphyxia rate, cardiac dysplasia rate, neonatal anaemia rate, neonatal mortality and the incidence of hyaline membrane disease were significantly lower than those of the control group, and the differences were statistically significant(P<0.05). Conclusion Expectant treatment for pregnant women with early-onset severe pre-eclampsia and fetal growth restriction does not increase the incidence of complications and is worthy of application.