彩色多普勒超声对慢性乙型肝炎肝纤维化的价值

The Value of Doppler Ultrasound of Liver Fibrosis in Chronic Hepatitis B

目的探究彩色多普勒超声对慢性乙型肝炎肝纤维化患者的诊断价值。方法选取96例慢性乙型肝炎肝纤维化患者、21例健康体检者作为研究对象,分别作为实验组、常规组。对两组研究对象均采取彩色多普勒超声检查。对比两组研究对象的检查结果。结果对慢性乙型肝炎肝纤维化相关指标采取多元logistic回归分析,发现常规组和实验组不同分期的门静脉内径、肝固有动脉峰值流速、门静脉峰值流速与慢性乙型肝炎肝纤维化具有相关性。门静脉内径、肝固有动脉峰值流速随着肝纤维的严重程度而增高,门静脉峰值流速随着肝纤维的严重程度而降低(P <0.05)。不同纤维化分期之间及常规组的脾动脉搏动指数差异无统计学意义(P> 0.05)。结论不同程度的肝纤维化患者的血流有明显差异,并且有慢性乙型肝炎肝纤维化患者和无肝病的健康受检者之间差异也十分明显。

Objective To explore the diagnostic value of color Doppler ultrasound in patients with chronic hepatitis B hepatic fibrosis. Methods 96 patients with chronic hepatitis B liver fibrosis and 21 healthy persons were selected as the study subjects, which were experimental group and routine group respectively. Both groups were examined by color Doppler ultrasound. The results of the two groups were compared. Results Multivariate logistic regression analysis was used to analyze the related indicators of hepatic fibrosis in chronic hepatitis B. It was found that the internal diameter of portal vein, the peak flow velocity of proper hepatic artery and the peak flow velocity of portal vein in different stages were correlated with hepatic fibrosis in chronic hepatitis B. The internal diameter of portal vein and the peak velocity of proper hepatic artery increased with the severity of hepatic fibers, while the peak velocity of portal vein decreased with the severity of hepatic fibers(P<0.05). There was no significant difference in splenic artery pulsation index between different stages of fibrosis and conventional group(P>0.05). Conclusion Blood flow in patients with varying degrees of liver fibrosis were significantly different liver fibrosis in patients with chronic hepatitis B and liver disease-free healthy difference is very obvious.