重症支气管哮喘呼吸衰竭行高流量氧疗治疗

Treatment of Severe Bronchial Asthma Respiratory Failure With High Flow Oxygen Therapy

目的探讨经鼻高流量氧疗对治疗重症支气管哮喘合并呼吸衰竭的疗效分析。方法选取2016年2月—2018年2月入我院重症医学科接受治疗的重症支气管哮喘合并呼吸衰竭的患者54例作为研究对象,观察患者行经鼻高流量氧疗治疗前,治疗后4 h、12 h、24 h、48 h的临床症状及结果。结果患者在接受高流量氧疗前的pH、PaO_2、PaCO_2、与治疗后4小时、12小时、24小时、48小时对比,患者的血气分析指标均得到改善,数据比较,差异均具有统计学意义(P <0.05)。结论重症支气管哮喘合并呼吸衰竭的患者行经鼻高流量氧疗治疗,可有效的改善患者的缺氧症状,改善血气分析指标,对患者而言,预后效果较好。

Objective To investigate the therapeutic effect of transnasal hyperflow oxygen therapy on severe bronchial asthma with respiratory failure. Methods From February 2016 to February 2018, 54 patients with severe bronchial asthma complicated with respiratory failure who were admitted to department of critical care medicine of our hospital were selected as the study subjects. The clinical symptoms and results were observed before and after treatment for 4, 12, 24 and 48 hours. Results The pH, PaO2, PaCO2 of patients before receiving high flow oxygen therapy, and the blood gas analysis indexes of patients after 4 hours, 12 hours, 24 hours and 48 hours of treatment were improved, and the data were compared, the difference was statistically significant(P<0.05). Conclusion The patients with severe bronchial asthma complicated with respiratory failure can be treated with transnasal hyperflow oxygen therapy, which can effectively improve the anoxia symptoms and blood gas analysis indexes.