双氯芬酸钠联合阿托品对肾结石绞痛患者的治疗效果

Treatment Effects of Diclofenac Sodium Combined With Atropine on Patients With Colic of Renal Calculi

目的观察双氯芬酸钠联合阿托品对肾结石绞痛患者的治疗效果。方法选择我院收治的肾结石患者120例作为研究对象。遵照随机数字表法,将其分为研究组(n=60,给予双氯芬酸钠栓+阿托品联合治疗)和对照组(n=60,给予阿托品治疗),比较两组患者的治疗效果、肾绞痛程度、负性情绪及不良反应。结果研究组患者的治疗总有效率为95.00%,高于对照组的81.67%,组间比较,差异具有统计学意义(P<0.05);治疗后30 min、60 min,两组VAS评分呈显著下降趋势(P<0.05),且研究组治疗后30 min、60 min的VAS评分均低于对照组,差异具有统计学意义(P <0.05);治疗后,两组SAS、SDS评分均显著下降(P <0.05),且治疗后研究组的SAS、SDS评分均低于对照组,差异具有统计学意义(P <0.05);两组不良反应情况比较,差异无统计学意义(P> 0.05)。结论双氯芬酸钠联合阿托品能够有效缓解肾结石患者绞痛症状,改善其负性情绪,不良反应小,利于预后。

Objective To observe the treatment effects of diclofenac sodium combined with atropine on patients with colic of renal calculi. Methods 120 cases of renal calculi in our hospital were selected as the research objects. According to the random number table method, they were divided into study group(n=60, given diclofenac sodium suppository + atropine combined therapy) and control group(n=60, given atropine treatment). The therapeutic effect, degree of renal colic, negative emotions and adverse reactions were compared between the two groups. Results The total effective rate of the study group was 95.00%, higher than that of the control group(81.67%). There was a significant difference between the two groups(P<0.05). After 30 minutes and 60 minutes of treatment, the VAS scores of the two groups showed a significant downward trend(P<0.05). The VAS scores of 30 minutes and 60 minutes after treatment in the study group were lower than those in the control group, and the difference was statistically significant(P<0.05). After treatment, the scores of SAS and SDS in both groups decreased significantly(P<0.05), and the scores of SAS and SDS in the study group were lower than those in the control group after treatment(P<0.05). There was no significant difference in adverse reactions between the two groups(P>0.05). Conclusion Diclofenac sodium combined with atropine can effectively alleviate the symptoms of colic in patients with renal calculi, improve their negative emotions, and have less adverse reactions, which is conducive to prognosis.