联合疗法对缺血性脑血管病的价值

The Value of Combined Therapy for Ischemic Cerebrovascular Disease

目的探讨阿司匹林联合氯吡格雷治疗缺血性脑血管病的临床效果。方法将我院收集的缺血性脑血管病的患者分为研究组与对照组。两组均给予常规治疗与阿司匹林,研究组在上述治疗方案上加用氯吡格雷。对比两组缺血性脑血管病治疗疗效;两组治疗前及治疗后NIHSS评分及Barthel活动能力。结果研究组和对照组缺血性脑血管病治疗有效率分别为90.00%、73.33%,组间比较,差异具有统计学意义(P<0.05);两组治疗后NIHSS评分与Barthel活动能力比较,差异均具有统计学意义(P<0.05)。结论小剂量阿司匹林联合氯吡格雷可以改善缺血性脑血管病患者神经功能,提高肢体能力的恢复,同时稳定动脉粥样硬化斑块。

Objective To investigate the clinical effect of aspirin combined with clopidogrel in the treatment of ischemic cerebrovascular disease.Methods The patients with ischemic cerebrovascular disease in our hospital were divided into study group and control group. Both groups were given routine treatment and aspirin, and the study group was given clopidogrel in the above treatment. The therapeutic effect of ischemic cerebrovascular disease, NIHSS score and Barthel activity were compared between the two groups before and after treatment. Results The effective rates of treatment of ischemic cerebrovascular disease in the study group and the control group were 90.00% and 73.33%, respectively. There was a significant difference between the two groups(P < 0.05). After treatment, the NIHSS score of the two groups was significantly different from Barthel’s activity ability(P < 0.05). Conclusion Low-dose aspirin combined with clopidogrel can improve the neurological function of patients with ischemic cerebrovascular disease, improve the recovery of limb function, and stabilize atherosclerotic plaque.