汉中市1778例肺癌病人临床病理特征分析

Analysis of clinicopathological features of 1 778 patients with lung cancer in Hanzhong

目的探讨汉中市肺癌病人的一般临床流行病学特征和病理类型分布,以初步了解肺癌的流行趋势。方法收集汉中市中心医院2013年至2017年收治且常驻汉中市各县区的原发性支气管肺癌住院患者,观察性别、年龄、来源地和病理类型等资料并进行分析。结果共收集符合观察对象的肺癌病例1 778人次,肺癌发病人数逐年增多,性别比相对稳定,以男性病人为主(P=0.983);年龄趋势上以老年患者为主(P=0.001),不同年龄段患者的性别构成有差异(P<0.001);病理类型上男性以鳞癌为主(P<0.001),女性以腺癌为主(P<0.001),青年以腺癌为主(P=0.041),老年以鳞癌为主(P=0.001);在地域上汉中市肺癌病人无明显差异(P=0.074)。结论汉中市肺癌病人性别比例相对稳定,以男性病人为主。男性患者由于烟酒的嗜好,随着年龄的增加,鳞癌患病情况逐年增加;女性由于烹饪等接触油烟导致患腺癌的比例更大。

Objective To investigate the general clinical epidemiological characteristics and pathological type distribution of lung cancer patients in Hanzhong, in order to understand the prevalence of lung cancer. Methods The inpatients with primary bronchogenic carcinoma who resided in Hanzhong and who were admitted to Hanzhong Central Hospital from 2013 to 2017 were investigated. Data were analyzed on gender, age, source region and pathological type. Results Totally 1 778 cases of lung cancer were observed. The incidence of lung cancer increased year by year, with stable sex ratio mainly male patients ( P = 0.983 ), and the age trend was mainly elderly patients ( P =0.001). The gender composition of patients in the age groups was different ( P <0.001). While for pathological pattern, the male was mainly with squamous cell carcinoma ( P <0.001), the female mainly with adenocarcinoma ( P <0.001), the young mainly with adenocarcinoma ( P = 0.041), and the senile was mainly with squamous cell carcinoma ( P =0.001). There was no significant difference for region in lung cancer patients in Hanzhong ( P =0.074). Conclusion The sex ratio of lung cancer patients in Hanzhong is relatively stable, mainly male patients. The morbidity of squamous cell carcinoma increases with the increase of age in male patients′ hobby of tobacco and alcohol. The proportion of women with adenocarcinoma is higher due to exposure to cooking fumes.