期刊文献+

抗苗勒氏管激素对多囊卵巢综合征患者卵泡发育的影响 被引量:2

下载PDF
导出
摘要 目的分析抗苗勒氏管激素对多囊卵巢综合征(PCOS)患者卵泡发育的影响。方法选取120例多囊卵巢综合征患者作为试验组,另选取同期健康志愿者和因输卵管因素或男方因素所致不孕的卵巢形态、功能正常者30例作为对照组。试验组给予二甲双胍治疗。比较试验组治疗前后的抗苗勒氏管激素水平与对照组的差别。结果治疗前,试验组患者的抗苗勒氏管激素水平为(52.1±6.4)pmol/L,高于对照组的(16.8±7.2)pmol/L,差异具有统计学意义(P<0.05);治疗后,试验组患者的抗苗勒氏管激素水平与对照组比较,差异无统计学意义(P>0.05)。结论抗苗勒氏管激素与多囊卵巢综合征患者的卵泡发育有一定的关系。
出处 《中国现代药物应用》 2019年第10期110-111,共2页 Chinese Journal of Modern Drug Application
基金 深圳市宝安区科技计划基础研究项目(项目编号:20180329093500653)
  • 相关文献

参考文献9

二级参考文献148

  • 1Teixeira J, Maheswaran S, Donahoe PK. Mtillerian inhibiting substance: An instructive developmental hormone with di- agnostic and possible therapeutic applications. Endocr Rev, 2001, 22(5):657-74.
  • 2Weenen C, Laven JS, von Bergh AR, et al. Anti-Miillerian hormone expression pattern in the human ovary: potential implications for initial and cyclic follicle recruitment. Mol Hum Reprod, 2004, 10(2):77-83.
  • 3Nilsson E, Rogers N, Skinner MK. Actions of anti-Mtillerian hormone on the ovarian transcriptome to inhibit primordial to primary follicle transition. Reproduction, 2007, 134(2):209-21.
  • 4Dumesic DA, Lesnick TG, Stassart JP, et al. InWafollicular anti- Mtillerian hormone levels predict follicle responsiveness to follicle-stimulating hormone (FSH) in normoandrogenic ovu-latory women undergoing gonadotropin releasing-hormone analog/recombinant human FSH therapy for in vitro fertiliza- tion and embryo transfer. Fertil Steril, 2009, 92(1):217-21.
  • 5Das M, Gillott DJ, Saridogan E, et al. Anti-MiJllerian hormone is increased in follicular fluid from unstimulated ovaries in women with polycysfic ovary syndrome. Hum Reprod, 2008, 23(9): 2122-6,.
  • 6Kevenaar ME, Themmen AP, van Kerkwijk AJ, et al. Variants in the ACVR1 gene are associated with AMH levels in women with polycystic ovary syndrome. Hum Reprod, 2009, 24(1): 241-9.
  • 7Crisosto N, Sir-Petermann T, Greiner M, et al. Testosterone- induced dowrtregulation of anti-Mtillerian hormone expressionin granulosa cells from small bovine follicles. Endocrine, 2009, 36(2):339-45.
  • 8Chen M J, Yang WS, Chen CL, et al. The relationship between anti-Mtillerian hormone, androgen and insulin resistance on the number of antral follicles in women with polycystic ovary syndrome. Hum Reprod, 2008, 23(4):952-7.
  • 9Nardo LG, Yates AP, Roberts SA, et al. The relationships be- tween AMH, androgens, insulin resistance and basal ovarian follicular status in non-obese subfertile women with and with- out polycystic ovary syndrome. Hum Reprod, 2009, 24(11): 2917-23.
  • 10Falbo A, Rocca M, Russo T, et al. Serum and follicular anti- MiJllerian hormone levels in women with polycystic ovary syndrome (PCOS) under metformin. J Ovarian Res, 2010, 3(1): 16-21.

共引文献242

同被引文献19

引证文献2

二级引证文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部