瘢痕子宫剖宫产术中用缩宫素联合马来酸麦角新碱预防产后出血的疗效

The efficacy of oxytocin combined with ergometrine maleate in the prevention of postpartum hemorrhage in cesarean section of scar uterus

目的探讨缩宫素联合马来酸麦角新碱在瘢痕子宫剖宫产术中对产后出血的影响。方法选取我院2016年5月~2018年5月收治的90例接受剖宫产分娩的孕妇作为研究对象,随机分为对照组和研究组,各45例。对照组给予缩宫素,观察组采用缩宫素联合马来酸麦角新碱治疗。比较两组产妇出血量及不良反应发生情况。结果研究组的手术时间、住院时间均显著短于对照组(P <0.05);研究组产后30min,产后2h及产后24h的出血量均显著少于对照组(P <0.05);研究组产后出血发生率低于对照组(P <0.05);手术前后,两组产妇的收缩压,舒张压和血氧饱和度比较差异均无统计学意义(P> 0.05);研究组术后不良反应发生率显著低于对照组(P <0.05)。结论麦角新碱联合缩宫素对产后出血有显著改善效果,可广泛应用于临产后剖宫产术宫缩乏力引起的产后出血。

Objective To investigate the effect of oxytocin combined with ergometrine maleate in the prevention of postpartum hemorrhage in cesarean section of scar uterus. Methods From May 2016 to May 2018,90 pregnant women who underwent cesarean section in our hospital were selected as the study subjects,they were randomly divided into control group and study group,45 cases in each group.The control group was given oxytocin,and the observation group was given oxytocin combined with ergometrine maleate.Amount of bleeding and occurrence of adverse reactions were compared between the two groups. Results The operative time and hospital stay in the study group were significantly shorter than the control group(P < 0.05);The amount of bleeding in the study group was significantly lower than the control group at 30 min,2 h and 24 h postpartum(P < 0.05),the incidence of postpartum hemorrhage in the study group was lower than the control group(P < 0.05).There was no significant difference in systolic pressure,diastolic pressure and degree of blood oxygen saturation between the two groups before and after operation(P > 0.05),and the incidence of postoperative adverse reactions in the study group was significantly lower than the control group(P < 0.05).Conclusion Ergonosine maleate combined with oxytocin can significantly improve postpartum hemorrhage,and can be widely used in postpartum hemorrhage caused by uterine atony during cesarean section.