膝关节骨关节炎患者生活质量的影响因素分析

Analysis of influencing factors of the quality of life in patients with osteoarthritis of the knee

目的:探讨膝关节骨关节炎(osteoarthritis of knee,KOA)患者生活质量的影响因素,为临床上改善KOA疾病的预后提供依据。方法:选择2017年1月至2018年7月廊坊市第四人民医院骨科接受治疗的100例KOA患者与100例非KOA健康人为观察对象,调查记录BMI分级、居住条件、劳动强度、遗传因素、抽烟、饮酒、饮茶、食用瓜果、体育锻炼、骨密度等信息。采用logistic法进行回归分析。结果:两组性别、年龄、民族、职业等各方面的构成差异无统计学意义(P>0.05)。两组BMI分级、居住条件、遗传因素、抽烟、饮酒、饮茶、食用瓜果、体育锻炼、骨密度分布差异有统计学意义(P<0.05)。Logistic回归分析表明:影响KOA患者生活质量的危险因素为居住条件不佳、BMI、遗传因素、饮酒、体育锻炼;保护因素是饮茶与食用瓜果。结论:BMI过高、居住条件不佳、KOA相关的遗传因素异常、有饮酒习惯、体育锻炼过量等均能影响KOA患者的生活质量。而经常饮茶、食用瓜果则可以提高KOA患者的生活质量。影响因素分析对于KOA疾病的临床管理和防治具有十分重要的指导意义。

Objective:To explore the influencing factors of the quality of life in patients with osteoarthritis of knee (KOA), in order to provide the basis for clinical improving the prognosis and recovery of KOA disease.Methods:A total of 100 patients with KOA and 100 no-KOA people from Jan 2017 to Jul 2018 were recruited as the study objects,the information was recorded and assessed in patients with KOA and health,such as BMI classification, living conditions,the intensity of labor,genetic factors,smoking,drinking,drinking tea,eating fruits,such as physical exercise,bone density information.The information was analyzed by the logistic regression.Results: There was no significant difference in the composition of gender,age,nationality and occupation between the 2 groups (P>0.05).BMI classification,living conditions,genetic factors,smoking,drinking,drinking tea,eating fruits,physical exercise,bone mineral density distribution show significant difference in the 2 groups (P<0.05).The risk factors influencing the quality of life of KOA patients were poor living conditions,BMI,genetic factors,alcohol consumption,and physical exercise.The protective factors were tea drinking and fruit consumption.Conclusion:The high BMI,poor living conditions,abnormal genetic factors related to KOA,drinking habits and excessive physical exercise could all affect the quality of life of KOA patients.The influencing factors analysis has an important guiding significance to the clinical management,prevention and the cure for KOA disease.