中国汉族人群血浆三酰甘油浓度与高血压相关:一项大样本横断面研究

Triglyceride associated with primary hypertension in Chinese Han ethnic population: A cross-sectional study

目的:探究中国汉族人群血浆三酰甘油(triglyceride,TG)浓度与高血压的相关性。方法:对3100例高血压病患者和2652例非高血压病患者进行横断面研究,以确定TG与高血压病的关系。结果:TG作为连续变量时,每升高1mmol/L,高血压病OR为1.113,95%CI1.039~1.193。TG作为分类变量时,以Q1作参考分位,随着TG水平的增加,高血压病OR逐步增加(Q2:1.128,95%CI0.914~1.392;Q3:1.249,95%CI1.009~1.545;Q4:1.553,95%CI1.242~1.941;Q5:1.745,95%CI1.362~2.236)。建议诊断高血压病与非高血压病的TG的切割值为1.17mmol/L。结论:中国汉族人群的血浆TG水平与高血压病的发生相关,且TG水平越高与高血压病的相关性越强。

Objective:To explore the correlation between triglyceride and hypertension in Chinese Han population. Methods:Cross-sectional study of 3 100 cases and 2 652 controls was performed for identifying the association of TG with hypertension.Results:On a continuous scale,the risk ratios for primary hypertension per 1 mmol/L higher TG concentrations were 1.113,95%CI 1.039-1.193.On a categorical scale,the odds ratios for hypertension were consistently and significantly stepwise increased with the increased TG quintiles (Q2:1.128,95%CI 0.914- 1.392;Q3:1.249,95%CI 1.009-1.545;Q4:1.553,95%CI 1.242-1.941;Q5:1.745,95%CI 1.362-2.236).The suggested TG cutoff for discriminating hypertension from non-hypertension was 1.17 mmol/L.Conclusion:The TG level is associated with primary hypertension.