获得性反应性穿通性胶原病的研究进展

Update of acquired reactive perforating collagenosis

反应性穿通性胶原病是一种罕见的以变性胶原被排出体外为特征的穿通性皮肤病,成人发病常有伴发疾病,称获得性反应性穿通性胶原病。该病较为罕见,国内外对于该病的流行病学研究较少,其病因可能与遗传、糖尿病、高血压等多种因素有关,但具体发病机制仍不清楚,其治疗主要包括药物疗法和物理疗法等。

Reactive penetrating collagenosis is a rare penetrating dermatosis characterized by the excretion of degenerated collagen.This disease usually develops in adulthood and is associated with systemic diseases which also known as acquired reactive penetrating collagenosis.The disease is rare,and there are few epidemiological studies on the disease at home and abroad.The etiological factors include inheritance diabetes hypertension and so on although pathogenesis is onknown.Its treatment mainly includes drug therapy and physical therapy,etc.