探究社区糖尿病合并高血压治疗中采用硝苯地平联合厄贝沙坦治疗的临床疗效

Exploring the Clinical Efficacy of Nifedipine Combined with Irbesartan in the Treatment of Diabetes Mellitus Complicated with Hypertension

目的研究分析硝苯地平和厄贝沙坦联合治疗糖尿病高血压的临床效果,为临床治疗提供参考依据。方法 2013年8月—2016年8月该院对糖尿病合并高血压患者86例进行了分析研究,将患者分成了对照组和观察者,均有43例,对照组使用厄贝沙坦治疗,观察组使用硝苯地平联合厄贝沙坦治疗,对两组的临床治疗效果进行比较分析。结果治疗前两组的空腹血糖和餐后2 h血糖对比差异无统计学意义(P>0.05),治疗后观察者的两项指标比对照组优秀(P<0.05)。观察者有42例治疗有效,对照组有36例治疗有效,结果差异有统计学意义(P<0.05)。观察者有2例不良反应病例,对照组有5例不良反应病例,结果差异有统计学意义(P<0.05)。结论硝苯地平和厄贝沙坦联合治疗糖尿病高血压的效果理想,患者的不良反应率比较低,临床中应用价值非常高,值得推广使用。

Objective To analyze the clinical effect of nifedipine combined with irbesartan in the treatment of diabetic hypertension, and to provide reference for clinical treatment. Methods From August 2013 to August 2016, 86 patients with diabetes mellitus complicated with hypertension were analyzed. The patients were divided into control group and observation group, 43 cases in the control group were treated with irbesartan. The observation group was treated with nifedipine combined with irbesartan, and the clinical effects of the two groups were compared and analyzed. Results There was no statistically significant difference in fasting blood glucose between the two groups before treatment and 2 hours after meal (P>0.05). The two indicators of the observation group after treatment were superior to the control group (P<0.05). 42 patients were effective in the observation group and 36 in the control group. The results were statistically significant (P<0.05). There were 2 cases of adverse reactions in the observation group and 5 cases of adverse reactions in the control group. The results were statistically significant (P<0.05). Conclusion The combination of nifedipine and irbesartan is effective in the treatment of diabetic hypertension. The adverse reaction rate of patients is relatively low, and the clinical application value is very high. It is worthy of popularization.