结核分枝杆菌潜伏感染的治疗:利大于弊还是弊大于利

Treatment for latent tuberculosis infection in China: advantages or disadvantages

结核病仍然是全球十大死因之一。结核分枝杆菌潜伏感染(LTBI)是指结核分枝杆菌感染人体后,未发生活动性结核病,但具有发展为活动性结核病的风险。文章针对LTBI治疗充分阐述利弊,并结合中国结核病现实状况,提出在中国需要进行逐步的完善相关人群的预防治疗,逐渐由点到面推广LTBI的治疗,把结核病消灭在LTBI状态,降低结核病发病率,达到世界卫生组织提出的2035年消灭结核病的目标。

Tuberculosis remains one of the top ten causes of death worldwide, which seriously endangered human health. Latent tuberculosis infection(LTBI) refers to the fact that there no active tuberculosis after human body is infected, but there is the risk of developing active tuberculosis. This article elaborates the advantages and disadvantages of LTBI treatment, and based on the reality of tuberculosis in China, it is suggested that the prevention and treatment of LTBI should be improved step by step and the treatment of LTBI should be promoted from are to point in China,so as to eliminate tuberculosis in latent infection, reduce the incidence of tuberculosis,and achieve the goal of END TB strategy by the World Health Organization by 2035.