正念减压干预对食管癌患者癌因性疲乏的影响

Effect of mindfulness-based stress reduction on cancer-related fatigue in patients with esophageal cancer

目的探讨正念减压干预对食管癌患者癌因性疲乏的影响。方法将120例食管癌患者采用随机数字表法分为两组,两组均予以常规干预,研究组在此基础上联合正念减压干预,观察8周。干预前后采用中文版简明疲劳量表评定癌因性疲乏状况,凯勒斯10量表、简版流调中心抑郁量表评定负性情绪,压力知觉量表评定压力知觉水平,并比较两组上述评分结果。结果干预后,两组中文版简明疲劳量表、凯勒斯10量表、简版流调中心抑郁量表及压力知觉量表评分均较干预前显著降低(P<0.01),研究组显著低于对照组(P<0.01)。结论正念减压干预有助于食管癌患者调节其感知压力水平,有效缓解其癌因性疲乏状况和负性情绪。

Objective To investigate the effect of mindfulness-based stress reduction(MBSR)on cancerrelated fatigue(CRF)in patients with esophageal cancer.Methods 120 patients with esophageal cancer were divided into two groups by the random number table method,and they were given routine intervention.The study group were additionally given MBSR intervention.Patients were observed for 8 weeks.The degree of CRF [Chinese version of brief fatigue inventory(BFI-C)],negative emotions [ 10-item Kessler Psychological Distress Scale(K10),the Center for Epidemiological Studies Depression Scale(CES-D-13)] and the perceived stress level [Chinese Perceived Stress Scale(CPSS)] were compared between the two groups before and after the intervention.And compare the two groups of the above score results.Results After intervention,scores of BFI-C,K10,CES-D-13 and CPSS in the two groups were decreased(P<0.01),and the study group was significantly lower than the control group(P<0.01).Conclusion MBSR can help patients with esophageal cancer adjust their perceived stress levels,effectively alleviate cancer-related fatigue and negative emotions.