顶空固相微萃取-气相色谱-串联质谱法测定水中2,4,6-三氯酚

Determination of 2,4,6-Trichlorophenol in Water by HS-SPME-GC-MS-MS

建立了顶空固相微萃取-气相色谱-串联质谱法(HS-SPME-GC-MS-MS)测定水中2,4,6-三氯酚的方法。优化条件下,在1.00~50.0μg/L质量浓度范围内线性响应良好(r^2=0.9991);检出限0.224μg/L,测定下限0.896μg/L;加标样相对标准偏差(RSD)为4.15%~6.24%;加标回收率为81.0%~115%;单个样品检测总时间<40min。该方法萃取与气相色谱-串联质谱分析在线一步完成,操作简便、灵敏度高、抗干扰性强,适用于地表水、生活饮用水、工业废水等水体中2,4,6-三氯酚的检测。

The determination method of 2,4,6-trichlorophenol in water was established by headspace solid-phase micro-extraction coupled with gas chromatography-tandem mass spectrometry (HS-SPME-GC-MS-MS).After the conditions were optimized,the linear relationship was good enough ( r^2 =0.999 1) from 1.0 to 50.0 μg/L.The method detection limit was 0.224 μg/L and the method quantification limit was 0.896 μg/L.The RSDs of the spiked water were 4.15%~6.24%,and the recovery rates were 81.0%~115%.The total detection time of each sample is less than 40 minutes.The extraction and GC-MS-MS analysis of the proposed method are done online in one step.The method is easily operational,highly sensitive and strong anti-interference.The method is suitable for the determination of 2,4,6-trichlorophenol in surface water,drinking water,industrial wastewater and so on.