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弥散加权成像上颅内动脉粥样硬化狭窄致首发缺血性脑卒中不同发病机制的危险因素 被引量:11

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摘要 目的探讨弥散加权成像(DWI)上颅内动脉继粥样硬化性狭窄(ICAS)致首发缺血性脑卒中不同发病机制的危险因素。方法对283例责任ICAS致首发缺血性脑卒中患者发病机制进行回顾性分析,比较其危险因素。结果穿支动脉闭塞(LBO)67例(23.67%),多发机制93例(32.86%),动脉到动脉栓塞(A-A)116例(40.99%)。高血压病史156例(56.52%),吸烟92例(34.78%),糖尿病病史66例(23.91%),代谢综合征病史59例(21.38%);受累血管大脑中动脉(MCA)116例(42.03%),多血管床105例(38.04%),前后循环105例(38.04%),大脑后动脉(PCA)93例(33.70%)。A-A与LBO组高血压病史、载脂蛋白(Apo)B、ApoB/ApoA1与多血管床受累显著低于多发机制(P均<0.05)。结论高血压、吸烟、糖尿病、代谢综合征是不同脑卒中机制常见主要危险因素,MCA、多血管床、前后循环、PCA是常见受累血管。ApoB、ApoB/ApoA1与多血管床受累是促进单一向多发机制演变主要危险因素。
出处 《中国老年学杂志》 CAS 北大核心 2019年第11期2598-2602,共5页 Chinese Journal of Gerontology
基金 山东省中医药科技发展计划项目(2017-223) 山东省医药卫生科技发展计划项目(2015WS0051) 徐州医科大学博士后启动基金(2015107026)
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  • 1中华医学会神经病学分会脑血管病学组急性缺血性脑卒中诊治指南撰写组.中国急性缺血性脑卒中诊治指南2010[J].中国医学前沿杂志(电子版),2010,2(4):50-59. 被引量:1819
  • 2Feigin VL,Forouzanfar MH,Krishnamurthi R,et al.Global and regional burden of stroke during 1990-2010:findings from the Global Burden of Disease Study 2010.Lancet,2014,383:245-254.
  • 3Koton S,Schneider AL,Rosamond WD,et al.Stroke incidence and mortality trends in US communities,1987 to 2011.JAMA,2014,312:259-268.
  • 4Niu JW,Gao S,Cui LY,et al.Intracranial atherosclerosis in Chinese young adult stroke patients.J Stroke Cerebrovasc Dis,2014,23:1519-1523.
  • 5Qian Y,Pu Y,Liu L,et al.Low HDL-C level is associated with the development of intracranial artery stenosis:analysis from the Chinese Intracranial Atherosclerosis(CICAS)study.PLoS One,2013,8:e64395.
  • 6Hao Z,Liu M,Wang D,et al.High blood pressure on admission in relation to poor outcome in acute ischemic stroke with intracranial atherosclerotic stenosis or occlusion.J Stroke Cerebrovasc Dis,2014,23:1403-1408.
  • 7Lei C,Wu B,Liu M,et al.Risk factors and clinical outcomes associated with intracranial and extracranial atherosclerotic stenosis acute ischemic stroke.J Stroke Cerebrovasc Dis,2014,23:1112-1117.
  • 8Lin Y,Zhang L,Bao J,et al.Risk factors and etiological subtype analysis of brainstem infarctions.J Neurol Sci,2014,338:118-121.
  • 9Men X,Li J,Zhang B,et al.Homocysteine and C-reactive protein associated with progression and prognosis of intracranial branch atheromatous disease.PLoS One,2013,8:e73030.
  • 10Kim JS,Nah HW,Park SM,et al.Risk factors and stroke mechanisms in atherosclerotic stroke:intracranial compared with extracranial and anterior compared with posterior circulation disease.Stroke,2012,43:3313-3318.

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