乙肝相关性肝癌患者血清五项指标联合诊断价值被引量：15

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摘要目的研究乙肝相关性原发性肝癌患者癌胚抗原(CEA)、α-L-岩藻糖苷酶(AFU)、恶性肿瘤特异性生长因子(TSGF)、γ-谷氨酰转肽酶同工酶(GGT)与甲胎蛋白(AFP)水平联合诊断的价值。方法选取118例乙肝相关性肝癌患者设为肝癌组,另分别选取114例同期健康体检者、116例乙肝肝硬化患者作为正常组、肝硬化组,对比三组受试者AFP、TSGF、AFU、GGT、CEA水平,并对比各项指标单独诊断及联合诊断乙肝相关性原发性肝癌的结果。结果肝癌组AFP、TSGF、AFU、GGT、CEA含量均明显高于肝硬化组,且肝硬化组AFP、TSGF、AFU、GGT、CEA含量明显高于正常组(P<0.05)。应用血清五项指标联合诊断乙肝相关性肝癌的灵敏度为88.1%,准确度为83.3%,特异度为80.9%,与AFP、TSGF、AFU、GGT、CEA等指标单项诊断结果比较明显增高(P<0.05)。结论 AFP、TSGF、AFU、GGT及CEA指标联合应用于乙肝相关性肝癌患者早期诊断,诊断准确率较高,且检测方便。

作者黄彩转周云黄远江吴丽群王伟先

机构地区海南医学院第二附属医院感染科

出处《中国老年学杂志》 CAS 北大核心 2019年第11期2653-2655,共3页 Chinese Journal of Gerontology

关键词甲胎蛋白乙肝相关性肝癌恶性肿瘤特异性生长因子肝硬化 Α-L-岩藻糖苷酶 γ-谷氨酰转肽酶同工酶癌胚抗原

分类号 R735.7 [医药卫生—肿瘤]

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