聚桂醇联合组织胶治疗胃底静脉曲张出血的临床效果

Clinical effect of lauromacrogol combined with tissue glue in the treatment of gastric varices bleeding

目的探讨聚桂醇联合组织胶治疗胃底静脉曲张破裂出血(GVB)的临床效果。方法选取我院收治的82例GVB患者为研究对象,按照治疗方式不同将其分为对照组(41例,组织胶治疗)与观察组(41例,聚桂醇+组织胶治疗)。比较两组患者的治疗效果。结果观察组治疗总有效率明显高于对照组(P<0.05)。两组患者的近期再出血率及并发症发生率无显著差异(P>0.05);观察组止血成功率高于对照组,远期再出血率低于对照组(P<0.05)。两组患者排胶率、最早排胶时间及排胶出血率无显著差异(P>0.05);观察组排胶出血时间短于对照组(P<0.05)。治疗后,两组躯体功能、肌体疼痛、生命力、社会功能、情感健康及心理健康评分均显著升高,且观察组明显高于对照组(P<0.05)。结论聚桂醇联合组织胶治疗GVB效果显著,其可更好地改善曲张静脉,提高止血成功率,降低远期再出血发生风险,改善患者生活质量,对患者的排胶规律影响较小,值得临床推广。

Objective To investigate the clinical effect of lauromacrogol combined with tissue glue in the treatment of gastric varices bleeding(GVB). Methods Eighty-two patients with GVB admitted in our hospital were selected as the study objects and divided into control group(41 cases, treated with tissue glue) and observation group(41 cases, treated with lauromacrogol +tissue glue) according to different treatment methods. The therapeutic effects of the two groups were compared. Results The total effective rate of treatment in the observation group was significantly higher than that of the control group(P<0.05). There were no significant differences in recent rebleeding rate and complication rate between the two groups(P>0.05). The success rate of hemostasis in the observation group was higher than that in the control group, and the long-term rebleeding rate was lower than that in the control group(P<0.05). There were no significant differences in gum discharge rate, earliest gum discharge time and the bleeding rate of gum discharge between the two groups(P>0.05).The bleeding time of gum discharge in the observation group was earlier than that in the control group(P <0.05). After treatment, the scores of physical function, body pain, vitality, social function, emotional health and mental health of the two groups significantly increased, and those in the observation group were significantly higher than the control group(P<0.05).Conclusion Lauromacrogol combined with tissue glue in the treatment of GVB has a significant effect. It can better improve varicose veins and the success rate of hemostasis, reduce the risk of long-term rebleeding, improve the quality of life of patients and has little influence on the regularity of gum drainage, which is worthy of clinical promotion.