宫腔镜下子宫内膜息肉摘除术后给予孕激素治疗对息肉复发的预防价值

Preventive Value of Progesterone Therapy after Hysteroscopic Endometrial Polypectomy on Polyp Recurrence

目的探讨宫腔镜下子宫内膜息肉摘除术后给予孕激素治疗对息肉复发的预防价值。方法选取2016年6月至2017年6月于我院行宫腔镜下子宫内膜息肉摘除术的子宫内膜息肉患者56例,随机分为两组各28例。对照组行宫腔镜下子宫内膜息肉摘除术后不作任何处理,观察组在宫腔镜下子宫内膜息肉摘除术后给予复方醋酸环丙孕酮片治疗。比较两组患者治疗后的异常子宫出血、息肉复发情况及治疗前后的子宫内膜厚度。结果治疗6个月后,观察组异常子宫出血改善率为89.29%,高于对照组的64.29%(P <0.05);观察组的息肉复发率为3.57%,低于对照组的28.57%(P <0.05)。治疗前,两组患者的子宫内膜厚度比较差异无统计学意义(P>0.05);治疗6个月后,两组患者子宫内膜厚度比较差异有统计学意义(P <0.05)。结论宫腔镜下子宫内膜息肉摘除术后给予孕激素治疗能够有效改善患者的子宫出血情况,降低息肉复发率,改善子宫内膜厚度。

Objective To explore the preventive value of progesterone therapy after hysteroscopic endometrial polypectomy on polyp recurrence. Methods 56 cases of endometrial polyp patients undergoing hysteroscopic endometrial polypectomy in our hospital from June2016 to June 2017 were selected and randomly divided into two groups, with 28 cases in each group. The control group did not received any treatment after hysteroscopic endometrial polypectomy. The observation group was treated with compound cyproterone acetate tablets after hysteroscopic endometrial polypectomy. The abnormal uterine bleeding and polyp recurrence after treatment, and the endometrial thickness before and after treatment of the two groups were compared. Results 6 months after treatment, the improvement rate of abnormal uterine bleeding of the observation group was 89.29%, higher than 64.29% of the control group(P<0.05);The polyp recurrence rate of the observation group was 3.57%, lower than 28.57% of the control group(P<0.05). Before treatment, no statistical difference was found in the endometrial thickness between the two groups(P >0.05). 6 months after treatment, statistical difference was found in the endometrial thickness between the two groups(P<0.05). Conclusions Progesterone therapy after hysteroscopic endometrial polypectomy can effectively improve the uterine bleeding of patients, reduce the polyp recurrence rate and improve the endometrial thickness.