丙酸倍氯米松与布地奈德治疗小儿感染性喉炎的疗效比较

Comparison on the Curative Effects of Beclomethasone Propionate and Budesonide in the Treatment of Children with Infectious Laryngitis

目的比较丙酸倍氯米松与布地奈德治疗小儿感染性喉炎的疗效。方法选择我院2017年6月至2018年6月收治的60例感染性喉炎患儿,随机分为两组各30例。研究组采用布地奈德治疗,对照组采用丙酸倍氯米松治疗,对比两组的治疗效果。结果研究组的咳嗽、发热、声音嘶哑、呼吸困难及喉梗阻消退时间均短于对照组(P <0.05)。治疗前,两组的CRP、 PCT水平比较差异无统计学意义(P>0.05);治疗后,研究组的CRP、 PCT水平均低于对照组(P <0.05)。研究组的不良反应发生率为3.33%,明显低于对照组的20.00%(P <0.05)。结论布地奈德治疗小儿感染性喉炎效果明显,能够促进相关症状快速消退,降低炎症水平,减少不良反应发生,为预后提供保障。

Objective To compare the curative effects of beclomethasone propionate and budesonide in the treatment of children with infectious laryngitis. Methods 60 cases of children with infectious laryngitis admitted to our hospital from June 2017 to June 2018 were selected and randomly divided into two groups, with 30 cases in each group. The study group was treated with budesonide, and the control group was treated with beclomethasone propionate. The treatment effects of the two groups were compared. Results The disappearance time of cough, fever, hoarseness, dyspnea and laryngeal obstruction of the study group were shorter than those of the control group(P<0.05).Before treatment, no statistical difference was found in the CRP and PCT levels between the two groups(P >0.05). After treatment, the CRP and PCT levels of the study group were lower than those of the control group(P<0.05). The incidence of adverse reactions of the study group was 3.33%, significantly lower than 20.00% of the control group(P<0.05). Conclusions Budesonide in the treatment of children with infectious laryngitis has significant effect, which can promote the rapid disappearance of related symptoms, reduce the level of inflammation and the occurrence of adverse reactions, and provide a guarantee for prognosis.