肠道微生物与衰老

Intestinal Microorganisms and Aging

越来越多的证据表明,肠道微生物的种类、数量在衰老过程中发生了微妙变化,影响着机体的衰老状态。其中,大脑和肠道微生物之间的双向调节机制肠-脑-轴通过调节炎症因子等方式影响着衰老性认知障碍。通过合理的膳食纤维、益生菌干预和菌群移植可以一定程度上调节肠道菌群的结构和数量,减少由肠道菌群失调引起的疾病,起到延缓衰老的作用。

More and more evidence shows that the type and quantity of intestinal microbes have undergone subtle changes during the aging process, affecting the aging state of the body. Among them, the two-way regulatory mechanism between the brain and the intestinal microflora gut-brain-axis affects senile cognitive impairment by regulating inflammatory factors. Through reasonable dietary fiber, probiotic intervention and microbial transplantation, the structure and quantity of intestinal flora can be adjusted to a certain extent, and diseases caused by dysbacteriosis of the intestinal flora can be reduced, which can delay aging.