人致病沙门菌流行趋势与耐药情况的研究进展

Advance on epidemiological trend and drug resistance of human pathogenic Salmonella

沙门菌可分为伤寒沙门菌与非伤寒沙门菌(NTS)。伤寒沙门菌感染是部分地区的地方病,发病率区域差距大,在高收入地区,发病率趋于稳定或呈下降趋势。NTS的发病率随区域的不同而有较大差异,但其造成的疾病负担呈上升趋势。沙门菌感染的主要治疗手段是抗生素,但随之而来的耐药问题不可避免,沙门菌的耐药率正逐渐上升,耐药谱也逐渐增宽。本文对人致病沙门菌的流行趋势及耐药情况的变化进行综述。

Salmonella is divided into Typhoid salmonella and non-typhoid salmonella. Typhoid salmonella infection is endemic in some areas, and the incidence varies greatly among different areas. In high-income areas, Salmonella infection rates are stable or declining. The incidence of non-typhoid salmonella varies greatly in different regions, but the burden of disease caused by non-typhoid salmonella is increasing. The main treatment of Salmonella infection is antibiotics, but the problem of drug resistance is inevitable. The drug resistance rate of Salmonella is gradually increasing,and the drug resistance spectrum is gradually broadening. This article reviews the epidemiological trends and drug resistance changes of human pathogenic Salmonella.