室性期前收缩患者左室质量指数与早搏负荷、血尿酸的相关性分析

Relationships between left ventricular myocardial mass index and PVC-burden and serum uric acid in patients with premature ventricular contractions

目的探讨室性期前收缩(premature ventricular complexes,PVCs)患者左室质量指数(left ventricular myocardial mass index,LVMI)与早搏负荷、血尿酸(serum uric acid,UA)的相关性。方法回顾性分析PVCs患者149例,根据LVMI水平分为单纯PVCs组(n=66)、PVCs合并左室肥厚(left ventricular hypertrophy,LVH)组(n=83),比较两组间早搏负荷、UA等参数的差异,并运用二元Logistic回归分析LVH的危险因素。结果与单纯PVCs组比较,PVCs合并LVH组早搏负荷、UA升高,差异有统计学意义(P<0.05);二元Logistic回归分析提示年龄、早搏负荷、UA均为发生左心室肥厚的危险因素(P<0.05)。结论PVCs患者LVMI与早搏负荷、UA相关,随PVCs加重,患者更易发生左室肥厚;对于早搏负荷重、尿酸升高的PVCs患者应监测心功能,及早予以干预。

Objective To study the relationships between left ventricular myocardial mass index(LVMI)and PVC-burden and serum uric acid(UA)in patients with premature ventricular contractions(PVCs).Methods Totally 149 patients with PVCs were retrospectively analyzed.All the patients were divided into 2 groups with LVMI:the PVCs group(n=66)and the PVCs with left ventricular hypertrophy(LVH)group(n=83).The PVC-burden and UA level were compared and the Logistic regression analyses were used to identify the risk factors of LVH.Results Compared with the PVCs group,the PVC-burden and UA were increased in the PVCs with LVH group(P<0.05,respectively).In a binary Logistic regression analysis,age,PVC-burden and UA were the risk factors of LVH in patients with PVCs.Conclusion The LVMI was closely related to PVC-burden and UA.With the increase of PVCs burden,the patients with PVCs were prone to suffer LVH.For patients with a heavy load of PVC-burden and high level of UA,the cardiac function should be monitored on early stage and the clinical intervention should be provided in time.