大小球囊联合扩张治疗颈动脉狭窄的近远期效果

Short-term and long-term effects of large balloon combined with small balloon dilatation in the treatment of carotid artery stenosis

目的分析大小球囊联合扩张治疗颈动脉狭窄的近远期疗效。方法选取于我院诊治的78例颈动脉严重狭窄患者为研究对象,根据随机数字表法将其分为联合组和对照组,各39例。联合组行大小球囊联合扩张术,对照组行大球囊扩张术。观察比较两组患者NIHSS评分、并发症发生情况、术后1、3、6、12个月患者血管狭窄情况。结果术后2周及1年,两组患者的NIHSS评分均显著降低,且联合组均低于对照组(P<0.05);联合组患者的并发症总发生率为7.69%,明显低于对照组的33.33%(P<0.05);术后1、3、6、12个月,两组患者血管狭窄率均明显降低,且术后6、12个月,联合组患者的血管狭窄率显著低于对照组(P<0.05)。结论大小球囊联合扩张治疗颈动脉狭窄能较好地改善患者的神经功能,降低手术并发症发生率,改善预后情况,具有较好的近远期疗效。

Objective To analyze the short-term and long-term effects of large balloon combined with small balloon dilatation in the treatment of carotid artery stenosis. Methods A total of 78 patients with severe carotid artery stenosis in our hospital were selected as study objects and divided into combined group and control group according to random number table method, with 39 cases in each group. The combined group was treated with large balloon combined with small balloon dilatation, and the control group were treated with large balloon dilatation. The NIHSS scores, incidences of complications and the vascular stenosis at 1, 3, 6, 12 months after operation were observed and compared. Results At 2 weeks and 1 year after operation, the NIHSS scores of the two groups decreased, and those in the combined group were significantly lower than the control group (P<0.05). The total incidence of complications in the combined group was 7.69%, which was significantly lower than 33.33% in the control group, and the difference was statistically significant (P<0.05). At 1, 3, 6, 12 months after operation, the vascular stenosis rates in the two groups significantly decreased, and those in the combined group were lower than the control group at 6, 12 months after operation (P<0.05). Conclusion The large balloon combined with small balloon dilatation in the treatment of carotid artery stenosis can improve the neurological function better, reduce the incidence of complication and improve the prognosis, which has good short-term and long-term effect.